{"title":"类固醇诱发18处骨缺血性坏死1例。","authors":"J W Milgram, L H Riley","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>A patient with idiopathic thrombocytopenia purpura who was treated with high dosage corticosteroids for ten years, developed 18 separate lesions of avascular necrosis in 12 different bones. Despite spontaneous revascularization of many of the lesions, subchrondral collapse caused symptomatic secondary degenerative arthritis in many joints. Pathological examination of both resected femoral heads showed no intravascular thrombosis.</p>","PeriodicalId":47342,"journal":{"name":"Bulletin of the Hospital for Joint Diseases","volume":"37 1","pages":"11-23"},"PeriodicalIF":0.4000,"publicationDate":"1976-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Steroid induced avascular necrosis of bones in eighteen sites: a case report.\",\"authors\":\"J W Milgram, L H Riley\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A patient with idiopathic thrombocytopenia purpura who was treated with high dosage corticosteroids for ten years, developed 18 separate lesions of avascular necrosis in 12 different bones. Despite spontaneous revascularization of many of the lesions, subchrondral collapse caused symptomatic secondary degenerative arthritis in many joints. Pathological examination of both resected femoral heads showed no intravascular thrombosis.</p>\",\"PeriodicalId\":47342,\"journal\":{\"name\":\"Bulletin of the Hospital for Joint Diseases\",\"volume\":\"37 1\",\"pages\":\"11-23\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"1976-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of the Hospital for Joint Diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the Hospital for Joint Diseases","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
Steroid induced avascular necrosis of bones in eighteen sites: a case report.
A patient with idiopathic thrombocytopenia purpura who was treated with high dosage corticosteroids for ten years, developed 18 separate lesions of avascular necrosis in 12 different bones. Despite spontaneous revascularization of many of the lesions, subchrondral collapse caused symptomatic secondary degenerative arthritis in many joints. Pathological examination of both resected femoral heads showed no intravascular thrombosis.
期刊介绍:
Bulletin of the NYU Hospital for Joint Diseases is always interested in receiving manuscripts on appropriate topics for possible publication. Articles may contain clinical or basic scientic information related to orthopaedic surgery, musculoskeletal, rheumatological, or neurological diseases. Case reports are also accepted