为药物发现设计基于规则的生命科学本体互操作环境

2005 Symposium on Applications and the Internet Workshops (SAINT 2005 Workshops) Pub Date : 2005-01-31 DOI:10.1109/SAINTW.2005.55

T. Kosaka, S. Date, H. Matsuda, S. Shimojo

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引用次数: 0

摘要

生命科学数据库可以加速医学发展。然而，这些数据库之间的多样性一直是研究人员查询这些数据库的一个问题。在这种情况下，本体的概念有望成为聚合这些数据库并掩盖其多样性的重要关键。本文讨论了在药物发现的背景下推导和描述生命科学本体之间关系的两种方法。尽管本体的设计目的是使一组术语相互关联，但是使用标准本体语言OWL很难使不同本体中的术语相互关联。本文阐述了一种新的基于规则的本体互操作方法。这种方法将适应Web上的各种本体，尽管它目前处于开发的第一阶段。

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Designing a Rule-Based Environment to Interoperate Life-Scientific Ontologies for Drug Discovery

Life-scientific databases can accelerate medicine. However, the diversity among these databases has been a problem for researchers who query these databases. Under this situation, the concept of ontology is expected to be an important key to aggregate these databases and conceal their diversity. This paper discusses two methods for deriving and describing relationships between life-scientific ontologies in a context of drug discovery. Although an ontology is designed to interrelate a set of terms, it is difficult to interrelate terms in different ontologies using a standard ontology language, OWL. This paper illustrates a new rule-based method for interoperating ontologies. This method will be adaptive to various ontologies on the Web, although it is currently in the first stage of development.

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2005 Symposium on Applications and the Internet Workshops (SAINT 2005 Workshops)

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