直接脑冷却治疗重型颅脑外伤

Z. Idris, Ang Song Yee, R. Kandasamy, A. A. Manaf, Mohd Hasyizan Hassan, W. M. Hassan
{"title":"直接脑冷却治疗重型颅脑外伤","authors":"Z. Idris, Ang Song Yee, R. Kandasamy, A. A. Manaf, Mohd Hasyizan Hassan, W. M. Hassan","doi":"10.5772/INTECHOPEN.84685","DOIUrl":null,"url":null,"abstract":"There are scientific evidences that hypothermia provides a strong neuroprotective effect on the brain following traumatic insults. In this chapter, we describe the pathophysiology of severe head injury with emphasis on benefits of hypothermia. To support these hypothetical or theoretical benefits, we describe our previous study with very encouraging findings done on severe head injuries, treated with direct focal brain cooling, and monitored with intracranial pressure, cerebral perfusion pressure, brain oxygenation, and brain temperature. This chapter ends with our current and still ongoing study in which one of its main objectives is to innovate a direct focal brain cooling machine. This chapter briefly explains the technical part of this cooling machine.","PeriodicalId":401062,"journal":{"name":"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment","volume":"82 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Direct Brain Cooling in Treating Severe Traumatic Head Injury\",\"authors\":\"Z. Idris, Ang Song Yee, R. Kandasamy, A. A. Manaf, Mohd Hasyizan Hassan, W. M. Hassan\",\"doi\":\"10.5772/INTECHOPEN.84685\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"There are scientific evidences that hypothermia provides a strong neuroprotective effect on the brain following traumatic insults. In this chapter, we describe the pathophysiology of severe head injury with emphasis on benefits of hypothermia. To support these hypothetical or theoretical benefits, we describe our previous study with very encouraging findings done on severe head injuries, treated with direct focal brain cooling, and monitored with intracranial pressure, cerebral perfusion pressure, brain oxygenation, and brain temperature. This chapter ends with our current and still ongoing study in which one of its main objectives is to innovate a direct focal brain cooling machine. This chapter briefly explains the technical part of this cooling machine.\",\"PeriodicalId\":401062,\"journal\":{\"name\":\"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment\",\"volume\":\"82 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-02-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5772/INTECHOPEN.84685\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/INTECHOPEN.84685","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

摘要

有科学证据表明,低温对创伤性损伤后的大脑有很强的神经保护作用。在本章中,我们描述了严重头部损伤的病理生理学,重点是低温治疗的好处。为了支持这些假设或理论上的益处,我们描述了我们之前的研究,在严重头部损伤中进行了非常令人鼓舞的发现,直接局部脑冷却治疗,并监测颅内压,脑灌注压,脑氧合和脑温度。本章以我们当前和仍在进行的研究结束,其主要目标之一是创新一种直接聚焦脑冷却机。本章简要介绍了该冷却机的技术部分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Direct Brain Cooling in Treating Severe Traumatic Head Injury
There are scientific evidences that hypothermia provides a strong neuroprotective effect on the brain following traumatic insults. In this chapter, we describe the pathophysiology of severe head injury with emphasis on benefits of hypothermia. To support these hypothetical or theoretical benefits, we describe our previous study with very encouraging findings done on severe head injuries, treated with direct focal brain cooling, and monitored with intracranial pressure, cerebral perfusion pressure, brain oxygenation, and brain temperature. This chapter ends with our current and still ongoing study in which one of its main objectives is to innovate a direct focal brain cooling machine. This chapter briefly explains the technical part of this cooling machine.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信