DNAr-Logic: A constructive DNA logic circuit design library in R language for Molecular Computing

This paper describes the DNAr-Logic: an implementation of a software package in R language that provides ease of use and scalability of the design process of digital logic circuits in molecular computing, more specifically, DNA computing. These devices may be used in-vitro, in-vivo, or even replace the CMOS technology in some applications. Using a technique known as DNA strand displacement reaction (DSD) in conjunction with chemical reaction networks (CRN's), DNA strands can be used as “wet” hardware to construct molecular logic circuits analogous to electronic digital projects. The circuits designed using the DNAr-Logic can be created in a constructive manner and simulated without requiring knowledge of chemistry or DSD mechanism. The package implements all the main logic gates. We describe the design of a majority gate (also available in the package) and a full-adder circuit that only uses this port. We describe the results and simulation of our design.