具有抗肿瘤活性的生物碱结构物质对神经系统作用的评价

Oct-Nov 2022 Pub Date : 2022-10-16 DOI:10.55529/jhtd.26.6.10

Y. Mirzaev, T. T. Khamroev, E. Ruzimov, B. N. Khandamov, S. Adizov

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引用次数: 2

摘要

吲哚类生物碱包括吡唑啉酮甲基碘和吡唑啉酮氯对酒精性睡眠的镇静作用，并采用Sonberg法研究了其对觉醒或恐惧的影响。在本研究中，吡唑啉甲基碘和吡唑啉氯通过增加酒精引起的睡眠时间来减少睡眠时间，在Sonberg法中，由于噪音和外界因素，实验动物的尿液和粪便的排泄量减少。这表明所研究的物质具有镇静作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Evaluation of the Effect on the Nervous System of Substances with an Alkaloid Structure Having Antitumor Activity

Indole alkaloids including sedative activity of pyrazolone iodine methylate and pyrazolone chloride were caused by alcohol sleep and feeling against arousal or fear effects were studied by the Sonberg method. In this study, pyrazoline iodine methylate and pyrazaline chloride reduced sleep time by increasing the sleep time caused by alcohol, in the Sonberg method, the excretion of urine and excrement by experimental animals decreased due to noise and external factors. This indicates that the studied substances have a calming effect.

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Oct-Nov 2022

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