2019年3月至9月“FUNDAPE”基金会帕金森病患者16周体育活动的好处

Rosa Susana Cajamarca Naula
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摘要

背景:帕金森病(PD)是一种神经退行性疾病,由黑质多巴胺能神经元的丧失来解释,最常见于60岁以上的人群。本研究的目的是分析运动和非运动症状的益处,这些益处是在厄瓜多尔帕金森基金会(FUNDAPE)的帕金森病患者进行为期16周的体育锻炼后发现的。方法:这是一项准实验性的干入性研究,选取17例帕金森氏病患者进行了为期16周的有氧运动,分析其对最大耗氧量、运动技能、平衡、认知、身体成分和抑郁症的影响。分析采用Wilconson“t检验”。置信区间为95%,误差5%。结果:最大耗氧量提高29.86%。脂肪质量百分比下降10.78%。肌重率提高4.58%。在不同的评估测试中,UPRDS的平均得分提高了8.29%;伯格量表平均得分提高6.25%;Ye- savage老年抑郁量表显示,PD病程≤5年组可能抑郁的比例从42.86%降至7.14%,病程≥5年组可能抑郁的比例从66.67%降至33.33%;至于福尔斯坦最小心理状态测试,我们没有发现任何好处。结论:本研究表明,在帕金森病患者中应用16周的有氧运动计划有统计学上显著的益处,与疾病的运动和非运动症状、身体成分和最大耗氧量有关。没有发现与该疾病相关的认知障碍相关的显著益处。年龄小于60岁的患者获益更大,病程少于5年的患者获益也更大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Beneficios de la actividad física durante un lapso de 16 semanas en pacientes con Enfermedad de Parkinson de la fundación “FUNDAPE”, Marzo–Septiembre 2019
BACKGROUND: Parkinson's disease (PD) is neurodegenerative, explained by the loss of dopaminergic neurons of the substantia nigra, affecting most commonly people over 60 years of age. The aim of this study was to analyze the benefits in both motor and non-motor symptoms, found after a 16-week pro- gram of physical activity in people with this disease who belong to the Parkinson Foundation of Ecuador (FUNDAPE). METHODS: This is a quasi-experimental interventional study, with a sample of 17 patients with Parkin- son’s disease diagnosis that went through a 16 week program of aerobic exercise, to analyze its impact on maximum oxygen consumption, motor skills, balance, cognition, body composition, and presence of depression. For the analysis, Wilconson “t-test” was applied. Confidence interval was 95%, 5% error. RESULTS: The maximum oxygen consumption improved 29.86%. The percentage of fat mass decreased 10.78%. The muscle weight percentage increased 4.58%. Regarding the different evaluated tests, the mean score for UPRDS improved 8.29%; the mean score for Berg Scale test improved 6.25%; regarding Ye- savage Geriatric Depression Scale, the percentage of patients with probable depression decreased from 42.86% to 7.14% in the group with PD of ≤5 years of evolution, and from 66.67% to 33.33% in the group with PD for than 5 years; regarding the Folstein Minimental State of Mind test, we found no benefits. CONCLUSION: This study showed that there are statistically significant benefits resulting from the appli- cation of a 16 week aerobic exercise program in patients with Parkinson’s disease, related to the motor and non-motor symptoms of the disease, body composition, and maximum oxygen consumption. No significant benefits were found in relation to the cognitive impairment associated with the disease. The benefits were greater in patients younger than 60 years of age, and were also greater in patients with less than 5 years of evolution of the disease.
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