伯基特淋巴瘤亚型的特征:散发性、地方性和免疫缺陷性

Julia Miotti Lara, Cristina Ferreira Ramos Rossetto
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摘要

伯基特淋巴瘤(BL)是一种非霍奇金淋巴瘤(NHL),其历史始于20世纪50年代,由外科医生丹尼斯·伯基特(Denis Burkitt)在非洲大陆观察到,其特征是淋巴结生发中心的Myc基因易位。它具有高度侵袭性和增生性,是人类肿瘤中体积翻倍最快的。它有三种已知的病因:地方性、散发性和免疫缺陷。目的:该项目旨在证明伯基特淋巴瘤的临床和流行病学差异,鉴于相似的病因。方法学:进行文献综述,涵盖临床病例研究的各种亚型,以便
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CARACTERIZAÇÃO DOS SUBTIPOS DE LINFOMA DE BURKITT: ESPORÁDICO, ENDÊMICO E POR IMUNODEFICIÊNCIA
Introduction: Burkitt’s Lymphoma (BL), whose history began in the 1950s through observations by the surgeon Denis Burkitt on the African continent, is a type of Non-Hodgkin’s Lymphoma (NHL) characterized by a translocation in the Myc gene within the germinal center of the lymph nodes. It is highly invasive and proliferative, making it the human tumor that doubles in size most rapidly. It has three known etiologies: endemic, sporadic, and immunodeficiency. Objective: The project aimed to demonstrate the clinical and epidemiological differences of Burkitt’s lymphoma, given the similarities between the etiologies. Methodology: A literature review was conducted, covering clinical case studies of the various subtypes, in order to
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