头颈癌的精准医疗

Hye-sung Park, J. Kang
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引用次数: 0

摘要

人类基因组分析和信息通信技术(ICT)的技术进步将“精准医疗”带入了我们的临床实践。精准医学是一种新颖的医疗方法,它基于包括个人遗传信息、疾病信息、生活方式信息等在内的可靠数据,通过精确细分患者群体,为每个人提供量身定制的个性化治疗。除了非小细胞肺癌之外,精准医学还具有应用于治疗一系列肿瘤的潜力,在这些肿瘤中,精准肿瘤学已经得到了积极的实践。在这篇文章中,我们回顾了头颈癌(HNC)的精准医疗,重点是肿瘤不可知性生物标志物和治疗方法,如NTRK, MSI-H/dMMR, TMB-H和BRAF V600E,这些药物最近都获得了美国食品和药物管理局(FDA)的批准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Precision Medicine in Head and Neck Cancer
Technological advancement in human genome analysis and ICT (information & communication technologies) brought ‘precision medicine’ into our clinical practice. Precision medicine is a novel medical approach that provides personalized treatments tailored to each individual by precisely segmenting patient populations, based on robust data including a person’s genetic information, disease information, lifestyle information, etc. Precision medicine has a potential to be applied to treating a range of tumors, in addition to non-small cell lung cancer, in which precision oncology has been actively practiced. In this article, we are reviewing precision medicine in head and neck cancer (HNC) with focus on tumor agnostic biomarkers and treatments such as NTRK, MSI-H/dMMR, TMB-H and BRAF V600E, all of which were recently approved by U.S. Food and Drug Administration (FDA).
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