希望褐藻I:希波克拉底筛选和抗炎评价。

Lloydia Pub Date : 1977-07-01

R P Iyer, J K Brown, M G Chaubal, M H Malone

{"title":"希望褐藻I:希波克拉底筛选和抗炎评价。","authors":"R P Iyer, J K Brown, M G Chaubal, M H Malone","doi":"","DOIUrl":null,"url":null,"abstract":"Hippocratic screening, in rats, of the whole root and extracts of Brunfelsia hopeana administered intraperitonially indicated that the whole root has CNS depressent activity and that the chloroform extract (F) which contains the basic or 'alkaloidal' fraction concentrates this activity. Extract (F) at an oral dose level of 100 mg/kg, was equally effective (w/w) as phenylbutazone in reducing carrageenin-induced pedal edema in rats.","PeriodicalId":18256,"journal":{"name":"Lloydia","volume":"40 4","pages":"356-60"},"PeriodicalIF":0.0000,"publicationDate":"1977-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Brunfelsia hopeana I: Hippocratic screening and antiinflammatory evaluation.\",\"authors\":\"R P Iyer, J K Brown, M G Chaubal, M H Malone\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hippocratic screening, in rats, of the whole root and extracts of Brunfelsia hopeana administered intraperitonially indicated that the whole root has CNS depressent activity and that the chloroform extract (F) which contains the basic or 'alkaloidal' fraction concentrates this activity. Extract (F) at an oral dose level of 100 mg/kg, was equally effective (w/w) as phenylbutazone in reducing carrageenin-induced pedal edema in rats.\",\"PeriodicalId\":18256,\"journal\":{\"name\":\"Lloydia\",\"volume\":\"40 4\",\"pages\":\"356-60\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1977-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lloydia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lloydia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

希波克拉底筛选，在大鼠中，整个根和提取物的腹腔内施用表明，整个根具有中枢神经系统抑制活性，氯仿提取物(F)含有碱性或“生物碱”部分浓缩这种活性。口服100 mg/kg剂量的提取物(F)与苯丁酮在减少卡拉胶诱导的大鼠足部水肿方面的效果相同(w/w)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Brunfelsia hopeana I: Hippocratic screening and antiinflammatory evaluation.

Hippocratic screening, in rats, of the whole root and extracts of Brunfelsia hopeana administered intraperitonially indicated that the whole root has CNS depressent activity and that the chloroform extract (F) which contains the basic or 'alkaloidal' fraction concentrates this activity. Extract (F) at an oral dose level of 100 mg/kg, was equally effective (w/w) as phenylbutazone in reducing carrageenin-induced pedal edema in rats.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Lloydia

自引率

0.00%

发文量