细胞毒性抗体的体外证明及其在角膜移植排斥反应中的可能作用。

Investigative ophthalmology Pub Date : 1976-06-01

P S Binder, J W Chandler, H E Kaufman

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引用次数: 0

摘要

在补体存在的情况下，兔角膜暴露于异源豚鼠抗兔抗体，并使用对硝基蓝四氮唑证明内皮细胞毒性损伤。讨论了这些抗体作为“阻断抗体”和细胞毒性抗体在角膜移植排斥过程中的可能作用。

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In vitro demonstration of cytotoxic antibodies and their possible role in corneal graft rejections.

Rabbit corneas were exposed to heterologous guinea pig anti-rabbit antibodies in the presence of complement and cytotoxic damage to the endothelium was demonstrated using para nitroblue tetrazolium. The possible role of such antibodies as "blocking antibodies" and as cytotoxic antibodies in the corneal graft rejection process are discussed.

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Investigative ophthalmology

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