{"title":"铊中毒对大鼠小脑影响的电镜研究","authors":"Mahdi Hasan, Iqbal Ashraf, V.K. Bajpai","doi":"10.1016/S0379-0738(78)80008-5","DOIUrl":null,"url":null,"abstract":"<div><p>Rats were given thallium acetate (5 mg elemental thallium/kg body weight) intraperitoneally daily for 7 days. The brain was fixed by perfusion-fixation and small pieces of the cerebellum were processed for electron microscopy. Variegated mitochondrial profiles, increased incidence of electron — dense bodies and proliferation of Golgi zones were observed in the thallium — poisoned rat corebellum. Multilamellar cytoplasmic bodies were discernible in the cerebellar cortex of the thallium-treated rats.</p></div>","PeriodicalId":75860,"journal":{"name":"Forensic science","volume":"11 2","pages":"Pages 139-146"},"PeriodicalIF":0.0000,"publicationDate":"1978-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80008-5","citationCount":"8","resultStr":"{\"title\":\"Electron microscopic study of the effects of thallium poisoning on the rat cerebellum\",\"authors\":\"Mahdi Hasan, Iqbal Ashraf, V.K. Bajpai\",\"doi\":\"10.1016/S0379-0738(78)80008-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Rats were given thallium acetate (5 mg elemental thallium/kg body weight) intraperitoneally daily for 7 days. The brain was fixed by perfusion-fixation and small pieces of the cerebellum were processed for electron microscopy. Variegated mitochondrial profiles, increased incidence of electron — dense bodies and proliferation of Golgi zones were observed in the thallium — poisoned rat corebellum. Multilamellar cytoplasmic bodies were discernible in the cerebellar cortex of the thallium-treated rats.</p></div>\",\"PeriodicalId\":75860,\"journal\":{\"name\":\"Forensic science\",\"volume\":\"11 2\",\"pages\":\"Pages 139-146\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1978-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0379-0738(78)80008-5\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Forensic science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0379073878800085\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0379073878800085","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Electron microscopic study of the effects of thallium poisoning on the rat cerebellum
Rats were given thallium acetate (5 mg elemental thallium/kg body weight) intraperitoneally daily for 7 days. The brain was fixed by perfusion-fixation and small pieces of the cerebellum were processed for electron microscopy. Variegated mitochondrial profiles, increased incidence of electron — dense bodies and proliferation of Golgi zones were observed in the thallium — poisoned rat corebellum. Multilamellar cytoplasmic bodies were discernible in the cerebellar cortex of the thallium-treated rats.
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