台湾新城疫病毒:II,多核性与病毒毒力的关系。

W F Chen, Y S Lu, M C Chen
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引用次数: 0

摘要

选取15株本地分离株和5株已知新城疫病毒毒株,检测其对鸡胚肾(CEK)细胞、鸡胚蛋感染单位(CE)的细胞病变作用、平均死亡时间毒力、CE和鸡的脑内和静脉致病性指标,以及在CEK和BHK-21单细胞中引起内融合(FFWI)或外融合(FFWO)多核增生的能力。不同病毒株在感染后15小时诱导细胞FFWI的能力与其对CE和雏鸡的毒力有关,但细胞FFWO似乎与菌株的毒力没有任何关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Newcastle disease virus in Taiwan: II, Relationship between polykaryocytosis and virus virulence.

Fifteen selcted local isolates and five known Newcastle disease virus strains were examined for their cytopathic effects in chick embryo kidney (CEK) cells, egg-infectious units in chick embryos (CE), virulence by mean death time, intracerebral and intravenous pathogenicity indexes for CE and chicks, and ability to cause polykaryocytosis of fusion from within (FFWI) or fusion from without (FFWO) in CEK and BHK-21 monolayer cells. The capacity of the different virus strains to induce cell FFWI at 15 hr post-infection was related to their virulence for CE and chicks, but cell FFWO did not seem to be any relationship with the virulence of the strains.

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