M. Pirtskhalava, Malkhaz Vakhania, T. Tavkhelidze, M. Gogodze, Tornike Mindiashvili, Mariam Kobiashvili, V. Mittova
{"title":"peropitoton perfoliatus L.蛋白提取物对四氯化碳致小鼠肝损伤的保护作用","authors":"M. Pirtskhalava, Malkhaz Vakhania, T. Tavkhelidze, M. Gogodze, Tornike Mindiashvili, Mariam Kobiashvili, V. Mittova","doi":"10.56580/geomedi33","DOIUrl":null,"url":null,"abstract":"This article demonstrates the hepatoprotective action of the protein extract of the aquatic plant Potamogeton perfoliatus L. based on the histopathologic changes in the liver of mice with CCl4-induced liver damage. Using the chromatography, 4 fractions of the protein extract were obtained. It has been suggested that a fourth fraction corresponding to low molecular weight protein should most likely exhibit hepatoprotective properties. SDS-PAGE of P. perfoliatus L. revealed a protein with molecular weight of 21 kDa corresponding to the fourth peak of a chromatogram.","PeriodicalId":261879,"journal":{"name":"MODERN ISSUES OF MEDICINE AND MANAGEMENT","volume":"46 13 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hepatoprotective effect of protein extract of the Potamogeton perfoliatus L. against carbon-tetrachloride-induced hepatic injury in mice\",\"authors\":\"M. Pirtskhalava, Malkhaz Vakhania, T. Tavkhelidze, M. Gogodze, Tornike Mindiashvili, Mariam Kobiashvili, V. Mittova\",\"doi\":\"10.56580/geomedi33\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This article demonstrates the hepatoprotective action of the protein extract of the aquatic plant Potamogeton perfoliatus L. based on the histopathologic changes in the liver of mice with CCl4-induced liver damage. Using the chromatography, 4 fractions of the protein extract were obtained. It has been suggested that a fourth fraction corresponding to low molecular weight protein should most likely exhibit hepatoprotective properties. SDS-PAGE of P. perfoliatus L. revealed a protein with molecular weight of 21 kDa corresponding to the fourth peak of a chromatogram.\",\"PeriodicalId\":261879,\"journal\":{\"name\":\"MODERN ISSUES OF MEDICINE AND MANAGEMENT\",\"volume\":\"46 13 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"MODERN ISSUES OF MEDICINE AND MANAGEMENT\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.56580/geomedi33\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"MODERN ISSUES OF MEDICINE AND MANAGEMENT","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.56580/geomedi33","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hepatoprotective effect of protein extract of the Potamogeton perfoliatus L. against carbon-tetrachloride-induced hepatic injury in mice
This article demonstrates the hepatoprotective action of the protein extract of the aquatic plant Potamogeton perfoliatus L. based on the histopathologic changes in the liver of mice with CCl4-induced liver damage. Using the chromatography, 4 fractions of the protein extract were obtained. It has been suggested that a fourth fraction corresponding to low molecular weight protein should most likely exhibit hepatoprotective properties. SDS-PAGE of P. perfoliatus L. revealed a protein with molecular weight of 21 kDa corresponding to the fourth peak of a chromatogram.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
