{"title":"dple从连接极性复合体协调顶端肌动球蛋白组装","authors":"A. Marivin, R. Ho, M. Garcia-Marcos","doi":"10.1083/jcb.202111002","DOIUrl":null,"url":null,"abstract":"Marivin et al. show how association of the protein DAPLE with PAR polarity complexes at cell–cell junctions maintains an apical cytoskeletal network in epithelial cells by simultaneously activating heterotrimeric G proteins and recruiting the actin-stabilizing protein CD2AP.","PeriodicalId":343306,"journal":{"name":"The Journal of Cell Biology","volume":"82 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"DAPLE orchestrates apical actomyosin assembly from junctional polarity complexes\",\"authors\":\"A. Marivin, R. Ho, M. Garcia-Marcos\",\"doi\":\"10.1083/jcb.202111002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Marivin et al. show how association of the protein DAPLE with PAR polarity complexes at cell–cell junctions maintains an apical cytoskeletal network in epithelial cells by simultaneously activating heterotrimeric G proteins and recruiting the actin-stabilizing protein CD2AP.\",\"PeriodicalId\":343306,\"journal\":{\"name\":\"The Journal of Cell Biology\",\"volume\":\"82 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Cell Biology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1083/jcb.202111002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Cell Biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1083/jcb.202111002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
DAPLE orchestrates apical actomyosin assembly from junctional polarity complexes
Marivin et al. show how association of the protein DAPLE with PAR polarity complexes at cell–cell junctions maintains an apical cytoskeletal network in epithelial cells by simultaneously activating heterotrimeric G proteins and recruiting the actin-stabilizing protein CD2AP.
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