局部牛油果治疗轻微复发性口疮溃疡的有效性:一项随机对照临床试验

S. Amer
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引用次数: 0

摘要

目的:复发性口腔溃疡(RAU)是一种常见的疾病,不同的治疗方法被建议根除或缩短溃疡复发的时间。本研究的目的是确定局部应用0.5%鳄梨凝胶治疗(RAU)的有效性。对象和方法:60例溃疡期RAU患者随机分为两组。第一组:患者局部服用0.5%牛油果凝胶,每日三次,持续7天。组i:患者接受局部安慰剂凝胶治疗,每日3次,连续7天。患者在治疗前首次就诊时以及治疗的第4天和第7天进行检查。结果:外用0.5%牛油果凝胶治疗轻微复发性口疮RAU溃疡的效果优于安慰剂凝胶,其减轻疼痛的效果优于单独使用安慰剂凝胶。接受0.5%牛油果凝胶治疗的患者比接受安慰剂治疗的患者红斑程度更轻,溃疡大小和愈合时间也更短。结论:局部牛油果凝胶可以减轻疼痛、红斑和溃疡的大小,并加速其愈合,是一种合理的治疗轻微RAU的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Effectiveness Of Topical Avocado In The Treatment Of Minor Recurrent Aphthous Ulceration: A Randomized Controlled Clinical Trial
Objective: Recurrent aphthous ulceration (RAU) is a common condition , Different treatment modalities have been suggested to either eradicate or reduce the duration of ulcer recurrences . Aim of this research was to determine the effectiveness of topically applied 0.5% avocado gel in the treatment of (RAU) . Subjects and method: Sixty patients in the ulcerative stage of RAU were divided at random among two groups . Group I: Patients received topical 0.5% avocado gel three times daily for seven days. GroupII : Patients received topical placebo gel three times daily for seven days. The patients were examined at the time of initial visit before treatment administration and on the fourth and the seventh day of treatment. Results : The results showed that topical 0.5% avocado gel were more effective than placebo gel in the management of minor recurrent aphthous RAU ulceration as it reduces the pain after its application more than the placebo gel alone. Patients on 0.5% topical avocado gel therapy revealed less degree of erythema, decrease in ulcer size and healing period than patients on the placebo therapy. Conclusion: Topical avocado gel may be considerd a reasonable treatment of minor RAU as it reduces pain,erythema and ulcers size and accelerates its healing .
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