Satyansh Singh, P. Yadav, Priyanshu Mishra, Asgar Shameem, Deepak Yadav
{"title":"药物发现","authors":"Satyansh Singh, P. Yadav, Priyanshu Mishra, Asgar Shameem, Deepak Yadav","doi":"10.33513/ppps/2001-20","DOIUrl":null,"url":null,"abstract":"The process of drug development is very expensive process due to high costs of R&D and human clinical tests. At present a new approach is being tried to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on the knowledge. The drugs discoveries are based on molecular biological targets and improve the therapy for disease, wide ranging dosages of the compounds are introduced to the cell line or animal in order to obtain preliminary efficacy and pharmacokinetic information. The process of drug discovery involves the identification of candidates, synthesis, characterization, screening & assay for therapeutic efficacy. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials.","PeriodicalId":265635,"journal":{"name":"Journal of Pharmacy Practice and Pharmaceutical Sciences","volume":"5 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Drug Discovery\",\"authors\":\"Satyansh Singh, P. Yadav, Priyanshu Mishra, Asgar Shameem, Deepak Yadav\",\"doi\":\"10.33513/ppps/2001-20\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The process of drug development is very expensive process due to high costs of R&D and human clinical tests. At present a new approach is being tried to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on the knowledge. The drugs discoveries are based on molecular biological targets and improve the therapy for disease, wide ranging dosages of the compounds are introduced to the cell line or animal in order to obtain preliminary efficacy and pharmacokinetic information. The process of drug discovery involves the identification of candidates, synthesis, characterization, screening & assay for therapeutic efficacy. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials.\",\"PeriodicalId\":265635,\"journal\":{\"name\":\"Journal of Pharmacy Practice and Pharmaceutical Sciences\",\"volume\":\"5 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-05-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmacy Practice and Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33513/ppps/2001-20\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmacy Practice and Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33513/ppps/2001-20","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The process of drug development is very expensive process due to high costs of R&D and human clinical tests. At present a new approach is being tried to understand how disease and infection are controlled at the molecular and physiological level and to target specific entities based on the knowledge. The drugs discoveries are based on molecular biological targets and improve the therapy for disease, wide ranging dosages of the compounds are introduced to the cell line or animal in order to obtain preliminary efficacy and pharmacokinetic information. The process of drug discovery involves the identification of candidates, synthesis, characterization, screening & assay for therapeutic efficacy. Once a compound has shown its value in these tests, it will begin the process of drug development prior to clinical trials.