{"title":"单侧性的增生","authors":"J. Kalish, G. Ferrero, A. Mussa","doi":"10.1093/med/9780190944896.003.0010","DOIUrl":null,"url":null,"abstract":"The chapter discusses body asymmetry occurring as an isolated clinical feature or as part of well-characterized syndromes. The term “lateralized overgrowth” has been recently introduced to describe conditions characterized by disproportionate growth of one side of the body that might be caused by hemihyperplasia and/or hemihypertrophy. The chapter also provides a brief clinical overview of the major syndromes associated with lateralized overgrowth and discusses the molecular anomalies causing this disorder. Prognosis of conditions characterized by lateralized overgrowth varies according to the underlying cause. Treatment and management of conditions characterized by lateralized overgrowth mainly focus on tumor surveillance and management of eventual difference of limb length. Leg-length discrepancy can be associated with significant morbidity and can negatively influence the quality of life.","PeriodicalId":210886,"journal":{"name":"Overgrowth Syndromes","volume":"61 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lateralized Overgrowth\",\"authors\":\"J. Kalish, G. Ferrero, A. Mussa\",\"doi\":\"10.1093/med/9780190944896.003.0010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The chapter discusses body asymmetry occurring as an isolated clinical feature or as part of well-characterized syndromes. The term “lateralized overgrowth” has been recently introduced to describe conditions characterized by disproportionate growth of one side of the body that might be caused by hemihyperplasia and/or hemihypertrophy. The chapter also provides a brief clinical overview of the major syndromes associated with lateralized overgrowth and discusses the molecular anomalies causing this disorder. Prognosis of conditions characterized by lateralized overgrowth varies according to the underlying cause. Treatment and management of conditions characterized by lateralized overgrowth mainly focus on tumor surveillance and management of eventual difference of limb length. Leg-length discrepancy can be associated with significant morbidity and can negatively influence the quality of life.\",\"PeriodicalId\":210886,\"journal\":{\"name\":\"Overgrowth Syndromes\",\"volume\":\"61 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Overgrowth Syndromes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/med/9780190944896.003.0010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Overgrowth Syndromes","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/med/9780190944896.003.0010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The chapter discusses body asymmetry occurring as an isolated clinical feature or as part of well-characterized syndromes. The term “lateralized overgrowth” has been recently introduced to describe conditions characterized by disproportionate growth of one side of the body that might be caused by hemihyperplasia and/or hemihypertrophy. The chapter also provides a brief clinical overview of the major syndromes associated with lateralized overgrowth and discusses the molecular anomalies causing this disorder. Prognosis of conditions characterized by lateralized overgrowth varies according to the underlying cause. Treatment and management of conditions characterized by lateralized overgrowth mainly focus on tumor surveillance and management of eventual difference of limb length. Leg-length discrepancy can be associated with significant morbidity and can negatively influence the quality of life.
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