可生物降解的聚合物针头,具有毛细管力收集血液的沟槽

S. Aoyagi, H. Izumi, Y. Isono, K. Makihira, M. Fukuda
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引用次数: 10

摘要

本文提出了一种生物可降解聚合物(聚乳酸,简称PLA)针头,它有一个收集血液的沟槽。采用微成型方法可以制备固体聚合物微针。然而,用这种方法制作空心针是困难的。沿微模塑针的中心线制造具有超高纵横比的长孔也是困难的。另一方面,在针表面制造沟槽是比较容易的。血液通过毛细管力沿该沟槽向上流动,无需泵送机构即可实现简单易行的采血。通过在硅模上设计凹槽的湿蚀刻方法,制备了一种直柄针。采用激光微加工的方法在针的顶表面制造出沟槽。实验评价了该针的采血性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biodegradable Polymer Needle Having a Trench for Collecting Blood by Capillary Force
This paper proposes a biodegradable polymer (Poly Lactic Acid, called as PLA) needle having a trench for collecting blood. A solid micro needle of polymer can be fabricated by micromolding method. However, a hollow needle is difficult to be fabricated by this method. It is also difficult to fabricate a long hole with ultra high aspect ratio along the centerline of a micromolded needle. On the other hand, it is comparatively easy to fabricate a trench on a needle surface. Blood runs up along this trench by capillary force, which realizes simple and easy blood collection without pumping mechanism. A needle with straight shank is fabricated by contriving wet etching method of a groove on a silicon die. A trench is fabricated on the top surface of the needle by laser micromachining. The performance of collecting blood of this needle is experimentally evaluated.
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