{"title":"脑外伤患者的镇静作用","authors":"Lorenzo Peluso, B. López, R. Badenes","doi":"10.5772/INTECHOPEN.85266","DOIUrl":null,"url":null,"abstract":"Sedation is an important topic in neurocritical patients. When compared with general intensive care unit and traumatic brain-injured patients, sedation has its therapeutic indications, such as management of intracranial pressure, treatment of status epilepticus, sedation for targeted temperature management patients and paroxysmal sympathetic activity. Nowadays, the assessment of sedation is done by neurological evaluation and new monitors based on electroencephalography signals that help the physician titrate the sedative agents. Therefore, the aim of this chapter is to discuss the main pharmacological properties of sedatives and analgesics, their proper indications related to pathophysiological issues and their titrations based on the abovementioned new technologies.","PeriodicalId":401062,"journal":{"name":"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment","volume":"32 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Sedation in TBI Patients\",\"authors\":\"Lorenzo Peluso, B. López, R. Badenes\",\"doi\":\"10.5772/INTECHOPEN.85266\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Sedation is an important topic in neurocritical patients. When compared with general intensive care unit and traumatic brain-injured patients, sedation has its therapeutic indications, such as management of intracranial pressure, treatment of status epilepticus, sedation for targeted temperature management patients and paroxysmal sympathetic activity. Nowadays, the assessment of sedation is done by neurological evaluation and new monitors based on electroencephalography signals that help the physician titrate the sedative agents. Therefore, the aim of this chapter is to discuss the main pharmacological properties of sedatives and analgesics, their proper indications related to pathophysiological issues and their titrations based on the abovementioned new technologies.\",\"PeriodicalId\":401062,\"journal\":{\"name\":\"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment\",\"volume\":\"32 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-04-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5772/INTECHOPEN.85266\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Traumatic Brain Injury - Neurobiology, Diagnosis and Treatment","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5772/INTECHOPEN.85266","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Sedation is an important topic in neurocritical patients. When compared with general intensive care unit and traumatic brain-injured patients, sedation has its therapeutic indications, such as management of intracranial pressure, treatment of status epilepticus, sedation for targeted temperature management patients and paroxysmal sympathetic activity. Nowadays, the assessment of sedation is done by neurological evaluation and new monitors based on electroencephalography signals that help the physician titrate the sedative agents. Therefore, the aim of this chapter is to discuss the main pharmacological properties of sedatives and analgesics, their proper indications related to pathophysiological issues and their titrations based on the abovementioned new technologies.
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