{"title":"蛋白质-蛋白质相互作用网络的拓扑特征分析","authors":"Yuanyuan Sun, Yujie Zhao, C. Tse, F. Lau","doi":"10.1109/IWCFTA.2012.36","DOIUrl":null,"url":null,"abstract":"The Protein-Protein Interaction networks are the typical complex biological networks, and the analysis of their topological characteristics is one of the most important and widely discussed research topics today. This paper analyzes the topological characteristics of a PPI network based on the theory of complex networks, focusing on degree distribution, average path length, network diameter, clustering coefficient, degree correlations as well as fractality. The experimental results show that this PPI network has the typical scale-free and small-world distributions, low clustering coefficient, negative correlation, but it has no fractal feature.","PeriodicalId":354870,"journal":{"name":"2012 Fifth International Workshop on Chaos-fractals Theories and Applications","volume":"129 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2012-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Analysis of the Topological Characteristics of a Protein-Protein Interaction Network\",\"authors\":\"Yuanyuan Sun, Yujie Zhao, C. Tse, F. Lau\",\"doi\":\"10.1109/IWCFTA.2012.36\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The Protein-Protein Interaction networks are the typical complex biological networks, and the analysis of their topological characteristics is one of the most important and widely discussed research topics today. This paper analyzes the topological characteristics of a PPI network based on the theory of complex networks, focusing on degree distribution, average path length, network diameter, clustering coefficient, degree correlations as well as fractality. The experimental results show that this PPI network has the typical scale-free and small-world distributions, low clustering coefficient, negative correlation, but it has no fractal feature.\",\"PeriodicalId\":354870,\"journal\":{\"name\":\"2012 Fifth International Workshop on Chaos-fractals Theories and Applications\",\"volume\":\"129 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-10-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2012 Fifth International Workshop on Chaos-fractals Theories and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IWCFTA.2012.36\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2012 Fifth International Workshop on Chaos-fractals Theories and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IWCFTA.2012.36","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Analysis of the Topological Characteristics of a Protein-Protein Interaction Network
The Protein-Protein Interaction networks are the typical complex biological networks, and the analysis of their topological characteristics is one of the most important and widely discussed research topics today. This paper analyzes the topological characteristics of a PPI network based on the theory of complex networks, focusing on degree distribution, average path length, network diameter, clustering coefficient, degree correlations as well as fractality. The experimental results show that this PPI network has the typical scale-free and small-world distributions, low clustering coefficient, negative correlation, but it has no fractal feature.