Juhyun Lee, N. Jen, Fei Yu, W. Dai, Hongyu Yu, T. Hsiai
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Flexible intravascular thermal sensors to assess atherosclerosis-mediated changes in hemodynamics
In this study, we introduced an in vivo convective heat transfer-based micro-electromechanical system (MEMS) sensor that measured real-time experimental vascular shear stress values in the aortas of New Zealand White rabbits (n=4). Experiments were performed to measure flow profile changes in response to hyper-cholesterol diet and an irregular tachycardia condition. We have shown that these conditions induce shear stress changes indicative of pre-atherosclerosis regions by the MEMS thermal sensor.
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