归一化压缩距离和进化距离的基因组序列:聚类结果的比较

M. L. Rosa, S. Gaglio, R. Rizzo, A. Urso
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引用次数: 6

摘要

基因组序列通常使用进化距离进行比较,这一过程意味着序列的一致性。长序列比对是一个耗时的过程,所获得的不相似度结果并不是一个度量。近年来,规范化压缩距离作为一种计算两个通用数字对象之间距离的方法被引入,它似乎是一种比较基因组字符串的合适方法。本文比较了利用进化距离和压缩距离得到的聚类和非线性映射,以了解两个距离集是否相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Normalised compression distance and evolutionary distance of genomic sequences: comparison of clustering results
Genomic sequences are usually compared using evolutionary distance, a procedure that implies the alignment of the sequences. Alignment of long sequences is a time consuming procedure and the obtained dissimilarity results is not a metric. Recently, the normalised compression distance was introduced as a method to calculate the distance between two generic digital objects and it seems a suitable way to compare genomic strings. In this paper, the clustering and the non-linear mapping obtained using the evolutionary distance and the compression distance are compared, in order to understand if the two distances sets are similar.
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