2019冠状病毒病大流行期间的女性健康

Y. Fedorchenko
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引用次数: 0

摘要

随着COVID-19在世界各地的发病率继续大幅上升,它对女性健康产生了深远影响。现有的数据表明,在中年组中,男性比女性表现出更大的疾病严重程度和/或死亡率,然而,这些差异似乎在老年患者中并不保留。临床医生应考虑诊断和治疗管理中的性别差异。COVID-19病毒感染的严重程度与细胞因子平衡密切相关,而细胞因子平衡不可避免地受到激素变化的影响。妇女在衰老过程中缺乏雌激素,在急性期及其后续阶段构成重大威胁,可能导致自身免疫或长期并发症。迫切需要研究COVID-19大流行期间的女性衰老,以减轻这些患者的免疫功能障碍,确定最佳做法,并制定健康促进策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FEMALE HEALTH AMIDST THE COVID-19 PANDEMIC
As COVID-19 morbidity rates continue to increase tremendously across the world, it has a profound effect on female health. The available data suggest that men demonstrate greater disease severity and/or mortality than women in the middle-aged group, however, these differences seem not to be preserved in the elderly patients. Clinicians should consider gender disparities in diagnostic and therapeutic management. The severity of COVID-19 viral infection is tightly linked with cytokine balance which is inevitably influenced by hormonal changes. Lack of estrogens during the ageing process in women poses a significant threat during the acute phase as well as in the sequel, which may result in autoimmunity or long-term complications. Research on female ageing amid the COVID-19 pandemic is urgently needed to alleviate immune dysfunction in these patients, define best practices, and develop health promotion strategies.
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