骨髓移植与孟加拉展望

A. Saleh
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引用次数: 0

摘要

供体的可用性是同种异体SCT的主要关注点,其成功与否主要取决于供体的可用性。完全匹配的HLA兄弟姐妹是最受欢迎的供体,但大约只有30%的病例匹配。对于剩下的大多数病例,我们必须依靠其他来源,如目前流行的单倍同卵捐献者、脐带血或无血缘关系的捐献者。全球领先的骨髓移植登记机构有:澳大利亚骨髓移植受体登记机构(ABMTRR)、国际血液和骨髓移植研究中心(CIBMTR)、奥地利登记机构(ASCTR)、捷克BMT登记机构、法国登记机构(SFGM)、德国登记机构(DRST)、意大利登记机构(GITMO)、荷兰登记机构(HOVON)、西班牙BMT登记机构(GETH)、瑞士登记机构(SBST)、土耳其BMT登记机构、英国登记机构(BSBMT)和Eurocord1。从这些登记处安排脐带血单位或无血缘关系的捐献者在后勤方面极其困难,而且费用也很高。为了克服这一障碍,我们需要建立一个全国性的骨髓登记处,通过这个登记处可以获得许多捐赠者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bone Marrow Transplant and Bangladesh Perspective
Availability of donors is the major concern for allogeneic SCT in which success mostly depends. Full matched HLA siblings are the most preferred donors but roughly it matches in around 30% cases. For the remaining majority cases we must depend on alternative sources like currently popular haplo-identical donors, cord blood or unrelated donors. Worldwide leading donor registries are: Australasian Bone Marrow Transplant Recipient Registry (ABMTRR), Centre for International Blood and Marrow Transplant Research (CIBMTR), the Austrian Registry (ASCTR), the Czech BMT Registry, the French Registry (SFGM), the German Registry (DRST), the Italian Registry (GITMO), the Dutch Registry (HOVON), the Spanish BMT Registry (GETH), the Swiss Registry (SBST), the Turkish BMT Registry and the British Registry (BSBMT) and Eurocord1. To arrange a cord unit or unrelated donor from these registries is exceedingly difficult in terms of logistics and costly as well. To overcome this obstacle, we need to establish a national marrow registry through which many donors could be available.
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