{"title":"辣木叶提取物对大鼠铅中毒的防治作用","authors":"K. Hussain, Samia M. Khaleil, F. A. El-Salam","doi":"10.21608/mjab.2019.116390","DOIUrl":null,"url":null,"abstract":"This study was carried out to evaluate the effect of Moringa leaves extracts for treatment the toxicity by Lead in rats. Lead toxicity often to various clinical conditions, Batteries, power cables, computer, water pipes, found in petroleum oil, coal and tobacco. Moringa leaves were found to contain antioxidants. (237.1 mg/g) phenols and (141.7 mg/g) flavones. Phenols were found to contain 23 phenolic compounds, vanillic, salicylic, and Catechins phenols are present in large amounts. Exposure to Lead increased the activity of liver enzymes AST, ALT and ALP while the level of albumin was decreased there is a significant increase in the level of urea and creatinine. The addition of the water and acetone extracts reduced the harmful effect of lead poisoning the treatment with Moringa leaf extracts improved the activity of antioxidant parameters (SOD,CAT and MDA),and decrease in the accumulation of lead in both liver and brain in the experimental rats.","PeriodicalId":280782,"journal":{"name":"Menoufia Journal of Agricultural Biotechnology","volume":"126 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"EFFECT OF MORINGA LEAVES EXTRACTS AGAINST POISONED BY PB IN RATS\",\"authors\":\"K. Hussain, Samia M. Khaleil, F. A. El-Salam\",\"doi\":\"10.21608/mjab.2019.116390\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study was carried out to evaluate the effect of Moringa leaves extracts for treatment the toxicity by Lead in rats. Lead toxicity often to various clinical conditions, Batteries, power cables, computer, water pipes, found in petroleum oil, coal and tobacco. Moringa leaves were found to contain antioxidants. (237.1 mg/g) phenols and (141.7 mg/g) flavones. Phenols were found to contain 23 phenolic compounds, vanillic, salicylic, and Catechins phenols are present in large amounts. Exposure to Lead increased the activity of liver enzymes AST, ALT and ALP while the level of albumin was decreased there is a significant increase in the level of urea and creatinine. The addition of the water and acetone extracts reduced the harmful effect of lead poisoning the treatment with Moringa leaf extracts improved the activity of antioxidant parameters (SOD,CAT and MDA),and decrease in the accumulation of lead in both liver and brain in the experimental rats.\",\"PeriodicalId\":280782,\"journal\":{\"name\":\"Menoufia Journal of Agricultural Biotechnology\",\"volume\":\"126 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Menoufia Journal of Agricultural Biotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21608/mjab.2019.116390\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Menoufia Journal of Agricultural Biotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/mjab.2019.116390","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
EFFECT OF MORINGA LEAVES EXTRACTS AGAINST POISONED BY PB IN RATS
This study was carried out to evaluate the effect of Moringa leaves extracts for treatment the toxicity by Lead in rats. Lead toxicity often to various clinical conditions, Batteries, power cables, computer, water pipes, found in petroleum oil, coal and tobacco. Moringa leaves were found to contain antioxidants. (237.1 mg/g) phenols and (141.7 mg/g) flavones. Phenols were found to contain 23 phenolic compounds, vanillic, salicylic, and Catechins phenols are present in large amounts. Exposure to Lead increased the activity of liver enzymes AST, ALT and ALP while the level of albumin was decreased there is a significant increase in the level of urea and creatinine. The addition of the water and acetone extracts reduced the harmful effect of lead poisoning the treatment with Moringa leaf extracts improved the activity of antioxidant parameters (SOD,CAT and MDA),and decrease in the accumulation of lead in both liver and brain in the experimental rats.