土耳其Kastamonu地区孕妇乙型和丙型肝炎血清阳性率测定

Enis Fuat Tüfekci, B. Çalışır, Melike Yaşar Duman, Ç. Kılınç
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引用次数: 0

摘要

目的:怀孕期间乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染有传播给新生儿的风险。因此,在许多国家对孕妇进行了常规的乙肝和丙肝筛查。本研究旨在揭示Kastamonu地区孕妇血清中HBsAg、anti-HBs和anti-HCV的患病率,并将获得的数据与土耳其进行的研究结果进行比较。方法:选取2022年1月至2023年1月期间到Kastamonu培训研究医院微生物实验室进行HBsAg、anti-HBs和anti-HCV检测的孕妇为研究对象。这些孕妇被分成两组,分别是24岁和24岁。在雅培Architect i2000SR仪器上使用化学发光微粒免疫分析法进行测试,并根据制造商的说明对结果进行评估。结果:HBsAg、anti-HBs和anti-HCV阳性率分别为0.5% (n=9/1712)、51.1% (n=874/1712)和0.1% (n=2/1713)。HBsAg阳性在不同年龄组间无显著差异(p < 0.05),而抗- hbbs阳性在24岁年龄组明显高于24岁年龄组(p < 0.002)。结论:结果显示,HBsAg和anti-HCV阳性率低于土耳其近年来的大多数研究,而anti-HBs阳性率高于大多数研究。在孕妇的第一次随访中继续进行常规HBV和HCV筛查是至关重要的,并鼓励抗hbs阴性的个体接种HBV疫苗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Determination of hepatitis B and hepatitis C seroprevalence in pregnant women in the Kastamonu region, Turkey
Aims: Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections during pregnancy have a risk of transmission to the newborn. Therefore, pregnant women are routinely screened for HBV and HCV in many countries. This study aimed to reveal the seroprevalence of HBsAg, anti-HBs, and anti-HCV in pregnant women in the Kastamonu region and to compare the obtained data with the results of studies conducted in Turkey. Methods: Pregnant women who applied to Kastamonu Training and Research Hospital Microbiology laboratory between January 2022 and January 2023 for HBsAg, anti-HBs, and anti-HCV tests were included in this study. The pregnant women were separated into two groups ?24 and >24 age groups. The tests were performed using the chemiluminescence microparticle immune assay method on the Abbott Architect i2000SR instrument, and the results were evaluated per the manufacturer’s instructions. Results: HBsAg, anti-HBs, and anti-HCV positivity were 0.5% (n=9/1712), 51.1% (n=874/1712), and 0.1% (n=2/1713), respectively. While there was no significant difference between age groups for HBsAg positivity (p>0.05), anti-HBs positivity was found to be significantly higher in the ?24 age group than in the >24 age group (p=0.002). Conclusion: The results showed that HBsAg and anti-HCV positivity was lower than in most studies conducted in recent years in Turkey, and anti-HBs positivity was higher than in most studies. It is essential to continue routine HBV and HCV screening in pregnant women’s first follow-up and encourage anti-HBs-negative individuals to be vaccinated against HBV.
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