Formulation and Evaluation of Anti-inflammatory Herbal gel using Sarcosteema acidum

Abstract-Inflammation is a pathophysiological response of living tissues to injuries that leads to the local accumulation of plasmatic fluid and blood cells. Although it is a defense mechanism, the complex events and mediators involved the inflammatory reaction can induce, maintain or aggravate many diseases. Therefore, the uses of anti-inflammatory agents are helpful in the therapeutic treatment of these pathologies. In this context, medicinal plants are widely used in folk medicine of many countries to treat differentinflammatoryconditionsand,inparticular, skin inflammations. Present work was designed to formulate herbal gel using extract of Sarcosteema acidumstem which provide better efficacy and to ensure biological evaluation of prepared herbal gel for safety and efficacy.