水杨酸三丁基锡衍生物抑菌抑菌活性研究

P. Mittal
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引用次数: 0

摘要

有机锡化合物通常用作杀菌剂。以不同的摩尔比合成了水杨酸三丁基锡(IV)的衍生物。采用元素分析和各种仪器技术对合成产物进行了检验。通过对金黄色葡萄球菌(gram +ve)和表皮葡萄球菌(gram +ve)大肠杆菌(Escherichia coli)的最小抑菌浓度(Minimum Inhibitory Concentration)来评价合成的衍生物的抑菌性能。合成的化合物对黑曲霉和白色念珠菌的抑菌效果以最小抑菌浓度进行评价。讨论表明,所得到的化合物在室温下是稳定的。这些化合物在抗菌和抗真菌活性方面优于配体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Studies on Antibacterial and Antifungal Activities of Some Derivatives of Tributyltin (IV) of Salicylic Acid
Organotin compounds are commonly used as biocides. Some derivatives of Tributyltin (IV) of salicylic acid have been synthesized in various molar ratios. Elemental analyses and various instrumental techniques were used to examine the synthesized products. The antibacterial properties of the synthesized derivatives were assessed using their Minimum Inhibitory Concentration values on both gram +ve (Staphylococcus aureus) and gram -ve (Staphylococcus epidermidis) bacteria (Escherichia coli). The synthesized compounds' antifungal investigations on Aspergillus niger and Candida albicans fungus were evaluated using their Minimum Inhibitory Concentration values. The discussion shows that the compounds so obtained were found stable at room temperature. These compounds outperformed the ligand in terms of antibacterial and antifungal activity.
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