Clinical Reports of Patients with Singi-hwan Teatment of Male Climateric Syndrome with AMS Questionnaire

The purpose of this study was to investigate the clinical results of the 10 male climateric syndrome cases while treated with Singi-hwan. All patients were treated with Singi-hwan two times a days for 5 weeks. We checked testosterone, PSA in blood, HRV and AMS questionnaire score. The questionnaire score was improved after taking Singi-hwan. Stress resistance and autonomic nervous system activity is increased, but there was no statistical significance except for ApEn. Taking Singi-hwan did not affect the serum concentration of testosterone, PSA and blood biochemical tests. The next placebo-controlled studies about late onset hypogonadism treated with Singi-hwan are needed. keywords : Singi-hwan(腎氣丸), Male Climateric Syndrome, AMS(Ageing Males‘ Symptoms) questionnaire, HRV(Heart Rate Variability)