Surgical treatment of necrotizing fasciitis in the myelodysplastic syndrome in a child

Myelodysplastic syndromes are clonal stem cell diseases characterized by hematopoietic dysplasia taking place in one or more myeloid cell lines, as well as by a high risk of progression to acute myeloid leukemia. This systemic disease is often accompanied by the violated microcirculation in the skin due to thrombosis of the terminal arteries leading to the formation of necrotic zones. The multicomponent nature of the disease requires a multidisciplinary approach to the treatment and staged surgical intervention. In this article, we present an example of a successful complex treatment of a 16-year-old girl with soft tissue necrosis of the perineum which developed because of the myelodysplastic syndrome.