COVID-19感染动脉血流数值分析

A. Krishnan, Anjana P. Anantharaman
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摘要

计算流体动力学在血流动力学的研究中已经成为相关的,而临床结果是具有挑战性的。本文讨论了冠状病毒感染患者通过动脉分叉的二维瞬时血流分析。所考虑的几何形状是一个动脉分叉,主干直径3毫米,有两个出口。左侧出口(较小)直径1.5毫米,右侧出口(较大)直径2毫米。主杆、左支、右支的长度分别固定为35mm、20mm、25mm。血液中发生的粘度变化导致血流的不同参数变化。血液流向较小的分支受到血液粘度变化的显著影响。得到了向较大出口扩展的高压区域和增加的速度。冠状动脉的时间平均壁剪应力(TAWSS)在90°分叉角处为10.4114 Pa,而正常动脉为2.45002 Pa。对于不同的分叉角度,发现75°角时正常动脉和冠状病变动脉的最大时间平均壁剪应力分别为2.46076 Pa和10.42542 Pa。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Numerical Analysis of Blood Flow through COVID-19 Infected Arteries
Computational Fluid Dynamics has become relevant in the study of hemodynamics, where clinical results are challenging to obtain. This paper discusses a 2-Dimensional transient blood flow analysis through an arterial bifurcation for patients infected with the Coronavirus. The geometry considered is an arterial bifurcation with main stem diameter 3 mm and two outlets. The left outlet (smaller) has a diameter of 1.5 mm and the right outlet (larger), 2 mm. The length of the main stem, left branch and right branch are fixed at 35 mm, 20 mm and 25 mm respectively. Viscosity change that occurs in the blood leads to different parametrical changes in blood flow. The blood flow towards the smaller branch is significantly affected by the changed blood viscosity. Extended regions of high pressure and increased velocity towards the larger outlet are obtained. The Time Averaged Wall Shear Stress (TAWSS) for the corona affected artery is found to be 10.4114 Pa at a 90° angle of bifurcation as compared to 2.45002 Pa of the normal artery. For varying angles of bifurcation, an angle of 75° was found to have a maximum Time Averaged Wall Shear Stress of 2.46076 Pa and 10.42542 Pa for normal and corona affected artery, respectively.
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