[播散性支气管源性癌患者的联合化疗(作者译)]。

Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology Pub Date : 1977-12-15 DOI:10.1007/BF00284303

C Gropp, K Havemann, W D Gassel, F Hess, R Prignitz, M Schmidt, C P Sodomann

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引用次数: 1

摘要

49例弥散性支气管源性癌(小细胞癌16例，鳞状癌17例，大细胞癌12例，腺癌4例)采用阿霉素、环磷酰胺、长春新碱和DTIC联合治疗。在一个随机系列(21例患者)中，将化疗单独与化疗加肝素进行比较。8例小细胞癌、5例大细胞癌和2例鳞状细胞癌获得部分缓解。对治疗有反应的患者的生存大于对治疗无反应的患者的生存。在接受额外肝素治疗的患者中，缓解持续时间和生存时间并不更长。

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[Combination chemotherapy in patients with disseminated bronchogenic carcinoma (author's transl)].

49 patients with disseminated bronchogenic carcinoma (small cell, 16;squamous cell, 17;large cell, 12;adeno, 4) were treated with a combination of adriamycin, cyclophosphamide, vincristine and DTIC. In a randomized series (21 patients) chemotherapy alone was compared to chemotherapy plus heparin. Partial remission was achieved in 8 patients with small cell carcinoma, in 5 patients with large carcinoma and in 2 patients with squamous cell carcinoma. The survival of patients who responded to therapy was greater than the survival of patients who did not respond to therapy. The duration of remission and the survival time was not longer in patients who had additional heparin therapy.

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Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology

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