老年NZB小鼠DNA迟发性超敏反应的自发发生。

J Pekárek, J Svejcar, J Rovenský, D Zitńan
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引用次数: 0

摘要

通过MIF的产生和对人工片段迁移的抑制,检测了NZB/Bl和NZB/Swiss Fl杂交小鼠脾淋巴细胞对DNA的敏感性。在老年小鼠组中发现阳性,这被认为是自发自身免疫过程的指示。讨论了这一过程的可能机理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spontaneous occurrence of delayed hypersensitivity to DNA in old NZB mice.

The sensitivity of NZB/Bl and NZB/Swiss Fl hybride mice spleen lymphocytes to DNA was examined using the MIF production and inhibition of migration from artificial fragment. The positivity was found in the group of old mice which was considered as an indication of spontaneous autoimmune process. The possible mechanism of this process is discussed.

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