[人类抗风湿(抗炎)药物评价标准]。

Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles Pub Date : 1978-10-23

F Delbarre, C Mery, J P Nakache, A de Géry, C Chastang

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引用次数: 0

摘要

在类风湿关节炎患者中进行的一项双盲、短期交叉试验中5种抗炎药物与安慰剂的比较使用和研究了15种测量方法。用经典的单维统计检验不可能区分它们之间的活性药物。多维分析(对应分析和判别分析)更灵敏，仅用11个标准就能区分出活性药物。

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[Criteria for the evaluation of the antirheumatic (antiinflammatory) drugs in man].

Comparison of 5 antiinflammatory drugs and placebo in a double blind, short term, cross-over trial conducted in patients suffering from rheumatoid arthritis. 15 measurements were used and studied. With classical unidimensional statistical tests it was not possible to discriminate active drugs between them. Multidimensional analysis (correspondance analysis and discriminant analysis) are more sensitive and allow us to distinguish active drugs with only 11 criterion.

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Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles

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