克罗恩病合并维生素B12过敏患者的一种安全新颖的门诊皮下维生素B12脱敏方案:一例报告。

IF 1.1 Q4 PHARMACOLOGY & PHARMACY

Current drug safety Pub Date : 2023-01-01 DOI:10.2174/1574886317666220328160026

Sara W Van Meerbeke, Andrej A Petrov, Arthur M Barrie Iii, Merritt L Fajt

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引用次数: 0

摘要

简介:虽然罕见，但有些患者可能会对维生素B12过敏。克罗恩病通常会导致严重的维生素B12缺乏症，尤其是那些接受回肠切除术的患者。在这些困难的情况下，可能需要维生素B12脱敏。病例介绍:在这里，我们报告了一例成功的门诊皮下维生素B12脱敏方案，患者为35岁女性，回肠切除术后有克罗恩病病史，随后缺乏维生素B12，并对皮下维生素B12过敏。结论:这是第一个在门诊安全进行的皮下维生素B12脱敏治疗方案。

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A Safe and Novel Outpatient Subcutaneous Vitamin B12 Desensitization Protocol in A Patient with Crohn's Disease and Vitamin B12 Allergy: A Case Report.

Introduction: Although rare, some patients may have a vitamin B12 allergy. Crohn's disease commonly leads to significant vitamin B12 deficiency, especially in those patients that have undergone ileal resection. In these difficult cases, vitamin B12 desensitization may be required.

Case presentation: Here, we report a successful case of a serial outpatient subcutaneous vitamin B12 desensitization protocol in a 35-year-old female with a past medical history of Crohn's disease status post ileal resection, subsequent vitamin B12 deficiency, and allergy to subcutaneous vitamin B12.

Conclusion: This is the first subcutaneous vitamin B12 desensitization protocol reported to have been safely performed in the outpatient setting.

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来源期刊

Current drug safety PHARMACOLOGY & PHARMACY-

CiteScore

2.10

自引率

0.00%

发文量

112

期刊介绍： Current Drug Safety publishes frontier articles on all the latest advances on drug safety. The journal aims to publish the highest quality research articles, reviews and case reports in the field. Topics covered include: adverse effects of individual drugs and drug classes, management of adverse effects, pharmacovigilance and pharmacoepidemiology of new and existing drugs, post-marketing surveillance. The journal is essential reading for all researchers and clinicians involved in drug safety.