与传染病病原体和宿主遗传学相关的伦理挑战。

IF 1.4 Q2 ETHICS
Richard Milne, Christine Patch
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引用次数: 3

摘要

2019冠状病毒病大流行证明了基因组技术在检测和监测传染病方面的潜力。病原体基因组学可能在基因组技术的未来研究和临床应用中发挥重要作用。然而,与人类遗传学不同,与实施传染病基因组学相关的具体伦理和社会挑战受到的关注相对较少。在本文中,我们对这一文献做出了贡献,重点关注使用这些技术对个人和社区的潜在后果。我们专注于与隐私、污名化、歧视和已知病原体、宏基因组学和宿主基因组学监测结果返回相关的挑战领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ethical Challenges Associated with Pathogen and Host Genetics in Infectious Disease.

The Covid-19 pandemic has demonstrated the potential of genomic technologies for the detection and surveillance of infectious diseases. Pathogen genomics is likely to play a major role in the future of research and clinical implementation of genomic technologies. However, unlike human genetics, the specific ethical and social challenges associated with the implementation of infectious disease genomics has received comparatively little attention. In this paper, we contribute to this literature, focusing on the potential consequences for individuals and communities of the use of these technologies. We concentrate on areas of challenges related to privacy, stigma, discrimination and the return of results in the cases of the surveillance of known pathogens, metagenomics and host genomics.

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来源期刊
CiteScore
2.30
自引率
16.70%
发文量
45
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