日本猫源犬小孢子菌的药敏试验。

IF 1.4 Q4 MYCOLOGY

Medical mycology journal Pub Date : 2023-01-01 DOI:10.3314/mmj.22-00014

Rui Kano, Mai Watanabe, Hitoshi Tsuchihashi, Takasuke Ogawa, Yumi Ogawa, Etsuko Komiyama, Yusuke Hirasawa, Masataro Hiruma, Shigaku Ikeda

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引用次数: 1

摘要

控制犬小孢子虫在宠物动物中的感染对预防人畜共患病具有重要意义。动物皮肤癣的治疗通常由伊曲康唑(ITZ)和特比萘芬(TRF)组成;然而，据报道，从猫皮肤癣病例中发现了一种耐trf的犬支原体菌株。在本研究中，我们检测了临床分离的犬支原体对拉武康唑(RVZ)和吕立康唑(LCZ)等新型抗真菌药物的体外敏感性。结果表明，RVZ和LCZ比ITZ和TRF更有效。因此，口服RVZ或外用LCZ可能是新的治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Antifungal Susceptibility Testing for Microsporum canis from Cats in Japan.

Control of infection caused by Microsporum canis in pet animals are important for prevention of zoonosis. Treatments for animal dermatophytosis have generally consisted of itraconazole (ITZ) and terbinafine (TRF); however, a TRF-resistant M. canis strain from a case of feline dermatophytosis has been reported. In the present study, we examined the in vitro susceptibility of clinical isolates of M. canis to new antifungal drugs, such as ravuconazole (RVZ) and luliconazole (LCZ). The results indicated that RVZ and LCZ are more effective than ITZ and TRF. Therefore, oral administration of RVZ or topical application of LCZ may serve as new treatment options.

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来源期刊

Medical mycology journal Medicine-Infectious Diseases

CiteScore

1.80

自引率

10.00%

发文量

期刊介绍： The Medical Mycology Journal is published by and is the official organ of the Japanese Society for Medical Mycology. The Journal publishes original papers, reviews, and brief reports on topics related to medical and veterinary mycology.