多重用药患者对药物基因组学检测的偏好:离散选择实验。

IF 1.7 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Cheng Chen, Melissa H Roberts, Dennis W Raisch, Todd A Thompson, Amy Bachyrycz, Matthew E Borrego
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引用次数: 0

摘要

目的:了解多重用药患者对药物基因组学(PGx)检测的偏好。材料与方法:设计并实施了一项面对面离散选择实验调查,调查对象是在阿尔伯克基(美国新墨西哥州)当地一家零售药店招募的多药合用成年患者。结果:共有 128 名符合条件的多种药物治疗患者完成了离散选择实验调查,他们更倾向于选择成本更低、保密性更好、更有把握确定最佳药物/剂量和副作用的 PGx 检验,以及可用于宣传其治疗需求的 PGx 检验(均为 p 结论:这是第一项能激发多种药物治疗患者选择 PGx 检验的研究:这是第一项在多种药物治疗患者中征求对 PGx 检测偏好的研究。研究发现,大多数多重用药患者愿意接受 PGx 检验,而他们的偏好主要受检验费用的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Preferences for pharmacogenomic testing in polypharmacy patients: a discrete choice experiment.

Aim: To elicit preferences for pharmacogenomic (PGx) testing in polypharmacy patients. Materials & methods: A face-to-face discrete choice experiment survey was designed and administered to adult polypharmacy patients recruited at a local retail pharmacy in Albuquerque (NM, USA). Results: A total of 128 eligible polypharmacy patients completed the discrete choice experiment survey and significantly preferred a PGx test with lower cost, better confidentiality and higher certainty of identifying best medication/dose and side effects and one that can be used to advocate for their treatment needs (all p < 0.01). Conclusion: This is the first study eliciting preferences for PGx testing among polypharmacy patients. The study found most polypharmacy patients were willing to take a PGx test and their preferences were mostly influenced by test cost.

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来源期刊
Personalized medicine
Personalized medicine 医学-药学
CiteScore
3.30
自引率
4.30%
发文量
49
审稿时长
6-12 weeks
期刊介绍: Personalized Medicine (ISSN 1741-0541) translates recent genomic, genetic and proteomic advances into the clinical context. The journal provides an integrated forum for all players involved - academic and clinical researchers, pharmaceutical companies, regulatory authorities, healthcare management organizations, patient organizations and others in the healthcare community. Personalized Medicine assists these parties to shape thefuture of medicine by providing a platform for expert commentary and analysis. The journal addresses scientific, commercial and policy issues in the field of precision medicine and includes news and views, current awareness regarding new biomarkers, concise commentary and analysis, reports from the conference circuit and full review articles.
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