经验莫匹罗星用于根除澳大利亚昆士兰州远北地区耐甲氧西林金黄色葡萄球菌定植的效用。

Q3 Medicine

Communicable diseases intelligence (2018) Pub Date : 2023-02-28 DOI:10.33321/cdi.2023.47.9

Isabel Guthridge, Stuart Campbell, Simon Smith, Josh Hanson

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引用次数: 1

摘要

耐甲氧西林金黄色葡萄球菌(MRSA)感染在远北昆士兰(FNQ)很常见，其发病率正在增加。澳大利亚指南建议使用包括局部莫匹罗星在内的非殖民化方案来减少复发感染。1997 - 2016年，FNQ地区对甲氧西林敏感的金黄色葡萄球菌(MSSA)分离株中有3932 / 15851株(24.8%)和MRSA分离株中有533/ 5134株(10.4%)对莫匹罗辛耐药。多因素分析中与莫匹罗星耐药相关的因素为MSSA分离株、年龄< 40岁、农村居住和女性。这些数据支持在FNQ中使用莫匹罗星进行MRSA去定植，尽管解决驱动金黄色葡萄球菌感染发生率的潜在健康社会决定因素仍然是当地医疗保健提供的优先事项。

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The utility of empirical mupirocin for eradication of methicillin-resistant Staphylococcus aureus colonisation in Far North Queensland, Australia.

Methicillin-resistant Staphylococcus aureus (MRSA) infections are common in Far North Queensland (FNQ) and their incidence is increasing. Decolonisation regimens that include topical mupirocin are recommended in Australian guidelines to reduce recurrent infection. Mupirocin resistance was identified in 3,932/15,851 (24.8%) methicillin-sensitive Staphylococcus aureus (MSSA) isolates and in 533/5,134 (10.4%) MRSA isolates from FNQ between 1997 and 2016. Factors associated with mupirocin resistance in multivariate analysis were an MSSA isolate, age < 40 years, rural residence and female gender. These data support the use of mupirocin in MRSA decolonisation in FNQ, although addressing the underlying social determinants of health that drive the incidence of S. aureus infections remain a priority for local healthcare provision.

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来源期刊

Communicable diseases intelligence (2018) Medicine-Medicine (all)

CiteScore

1.90

自引率

0.00%

发文量