血糖 "诊断价值的演变:找到识别葡萄糖动态变化的最佳点。

IF 29.9 1区 医学 Q1 PHYSIOLOGY
Physiological reviews Pub Date : 2023-01-01 Epub Date: 2022-05-30 DOI:10.1152/physrev.00015.2022
Faidon Magkos, Dominic N Reeds, Bettina Mittendorfer
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引用次数: 0

摘要

本文概述了上个世纪高血糖定义的演变,以及导致空腹和餐后高血糖的葡萄糖动态变化。我们讨论了对调节葡萄糖在血液循环中的出现及其被组织和器官摄取和代谢的因素和途径进行的广泛的机理和生理学研究是如何促进我们对不同类型高血糖的理解的、即糖尿病前期和糖尿病及其亚型(空腹血浆葡萄糖受损、糖耐量受损、合并空腹血浆葡萄糖受损、糖耐量受损、1 型糖尿病、2 型糖尿病、妊娠糖尿病)、它们与医疗并发症的关系以及如何预防和治疗高血糖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evolution of the diagnostic value of "the sugar of the blood": hitting the sweet spot to identify alterations in glucose dynamics.

In this paper, we provide an overview of the evolution of the definition of hyperglycemia during the past century and the alterations in glucose dynamics that cause fasting and postprandial hyperglycemia. We discuss how extensive mechanistic, physiological research into the factors and pathways that regulate the appearance of glucose in the circulation and its uptake and metabolism by tissues and organs has contributed knowledge that has advanced our understanding of different types of hyperglycemia, namely prediabetes and diabetes and their subtypes (impaired fasting plasma glucose, impaired glucose tolerance, combined impaired fasting plasma glucose, impaired glucose tolerance, type 1 diabetes, type 2 diabetes, gestational diabetes mellitus), their relationships with medical complications, and how to prevent and treat hyperglycemia.

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来源期刊
Physiological reviews
Physiological reviews 医学-生理学
CiteScore
56.50
自引率
0.90%
发文量
53
期刊介绍: Physiological Reviews is a highly regarded journal that covers timely issues in physiological and biomedical sciences. It is targeted towards physiologists, neuroscientists, cell biologists, biophysicists, and clinicians with a special interest in pathophysiology. The journal has an ISSN of 0031-9333 for print and 1522-1210 for online versions. It has a unique publishing frequency where articles are published individually, but regular quarterly issues are also released in January, April, July, and October. The articles in this journal provide state-of-the-art and comprehensive coverage of various topics. They are valuable for teaching and research purposes as they offer interesting and clearly written updates on important new developments. Physiological Reviews holds a prominent position in the scientific community and consistently ranks as the most impactful journal in the field of physiology.
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