基于免疫分析的霉菌毒素分析和毒物基因组学技术的最新进展。

IF 2.6 3区 农林科学 Q2 FOOD SCIENCE & TECHNOLOGY
Winnie-Pui-Pui Liew, Mohd-Redzwan Sabran
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引用次数: 3

摘要

霉菌毒素在食品和饲料中的共存和积累构成了食品安全、粮食安全和公共卫生的重大问题。准确、灵敏的霉菌毒素分析既可避免毒素污染,又可减少因假阳性结果造成的食物浪费。本文综述了多种真菌毒素检测方法的最新进展,主要依赖于免疫分析技术。在真菌毒素分析中集成了先进的免疫分析技术,可以同时检测多种真菌毒素,提高结果的质量。它强调了毒物基因组学作为利用计算方法来绘制分子事件和生物过程的危害评估的新方法。事实上,毒物基因组学是了解真菌毒素暴露对健康影响的有力工具,因为它提供了对真菌毒素暴露导致疾病的机制的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies.

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies.

Recent advances in immunoassay-based mycotoxin analysis and toxicogenomic technologies.

The co-occurrence and accumulation of mycotoxin in food and feed constitutes a major issue to food safety, food security, and public health. Accurate and sensitive mycotoxins analysis can avoid toxin contamination as well as reduce food wastage caused by false positive results. This mini review focuses on the recent advance in detection methods for multiple mycotoxins, which mainly depends on immunoassay technologies. Advance immunoassay technologies integrated in mycotoxin analysis enable simultaneous detection of multiple mycotoxins and enhance the outcomes' quality. It highlights toxicogenomic as novel approach for hazard assessment by utilizing computational methods to map molecular events and biological processes. Indeed, toxicogenomic is a powerful tool to understand health effects from mycotoxin exposure as it offers insight on the mechanisms by which mycotoxins exposures cause diseases.

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来源期刊
Journal of Food and Drug Analysis
Journal of Food and Drug Analysis 医学-食品科技
CiteScore
6.30
自引率
2.80%
发文量
36
审稿时长
3.8 months
期刊介绍: The journal aims to provide an international platform for scientists, researchers and academicians to promote, share and discuss new findings, current issues, and developments in the different areas of food and drug analysis. The scope of the Journal includes analytical methodologies and biological activities in relation to food, drugs, cosmetics and traditional Chinese medicine, as well as related disciplines of topical interest to public health professionals.
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