{"title":"补骨脂活性类黄酮化合物“茯苓素”在医学领域的生物学意义、疗效及分析研究","authors":"Dinesh Kumar Patel","doi":"10.2174/1871526522666220825160906","DOIUrl":null,"url":null,"abstract":"BACKGROUND Flavonoidal class phytochemicals are the best examples of secondary metabolite found to be present in the different natural sources, including 'fruits, grains, vegetables, broccoli, tea, berries, wine, strawberries, apple, grapes, lettuce and citrus fruit. Natural products are the rich source of flavonoidal compounds present in our diet source. OBJECTIVE Flavonoidal class chemical can be sub categorized into chalcones, isoflavone, flavonols, catechin, flavones, flavanones, and anthocyanidin with respect to their basic chemical structures. Psoralea corylifolia L. belongs to the family Fabaceae is an herbal medicine used in traditional Chinese Medicine for the treatment of inflammatory disorders, bacterial infections and cancerous disorders. METHODS In the present work, scientific data has been collected from different databases and analyzed in order to know the therapeutic potential of corylin in medicine. Different scientific databases such as Google, Scopus, PubMed, Science Direct etc., have been searched to collect the needed scientific information of corylin. Scientific information of corylin has been collected in the present work in order to know the pharmacological activities and medicinal uses of corylin in the scientific fields. However, analytical techniques data of corylin have also been collected and analyzed for standardization of Psoralea corylifolia and other medicinal plants. RESULTS Scientific data analysis of research works revealed the medicinal importance of Psoralea corylifolia and its important phytoconstituents corylin in the medicine. Scientific data analysis revealed that corylin is a flavonoidal class phytochemical found to be present in the nuts of Psoralea corylifolia L. Biological importance of corylin in bone differentiation, bone growth, osteoporosis have been proven in the scientific research work. Anti-inflammatory, anti-oxidant and antitumor activity of corylin has been also mentioned in the medicine. Biological importances of corylin in hyperlipidemia, insulin resistance, atherosclerosis, hepatocellular carcinoma and neurodisorders have also been presented in this work. CONCLUSION Scientific data analysis revealed the biological importance and therapeutic potential of corylin in the medicine.","PeriodicalId":13678,"journal":{"name":"Infectious disorders drug targets","volume":"23 1","pages":"e250822208005"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biological Importance, Therapeutic Benefits, and Analytical Aspects of Active Flavonoidal Compounds 'Corylin' from Psoralea corylifolia in the Field of Medicine.\",\"authors\":\"Dinesh Kumar Patel\",\"doi\":\"10.2174/1871526522666220825160906\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"BACKGROUND Flavonoidal class phytochemicals are the best examples of secondary metabolite found to be present in the different natural sources, including 'fruits, grains, vegetables, broccoli, tea, berries, wine, strawberries, apple, grapes, lettuce and citrus fruit. Natural products are the rich source of flavonoidal compounds present in our diet source. OBJECTIVE Flavonoidal class chemical can be sub categorized into chalcones, isoflavone, flavonols, catechin, flavones, flavanones, and anthocyanidin with respect to their basic chemical structures. Psoralea corylifolia L. belongs to the family Fabaceae is an herbal medicine used in traditional Chinese Medicine for the treatment of inflammatory disorders, bacterial infections and cancerous disorders. METHODS In the present work, scientific data has been collected from different databases and analyzed in order to know the therapeutic potential of corylin in medicine. Different scientific databases such as Google, Scopus, PubMed, Science Direct etc., have been searched to collect the needed scientific information of corylin. Scientific information of corylin has been collected in the present work in order to know the pharmacological activities and medicinal uses of corylin in the scientific fields. However, analytical techniques data of corylin have also been collected and analyzed for standardization of Psoralea corylifolia and other medicinal plants. RESULTS Scientific data analysis of research works revealed the medicinal importance of Psoralea corylifolia and its important phytoconstituents corylin in the medicine. Scientific data analysis revealed that corylin is a flavonoidal class phytochemical found to be present in the nuts of Psoralea corylifolia L. Biological importance of corylin in bone differentiation, bone growth, osteoporosis have been proven in the scientific research work. Anti-inflammatory, anti-oxidant and antitumor activity of corylin has been also mentioned in the medicine. Biological importances of corylin in hyperlipidemia, insulin resistance, atherosclerosis, hepatocellular carcinoma and neurodisorders have also been presented in this work. CONCLUSION Scientific data analysis revealed the biological importance and therapeutic potential of corylin in the medicine.\",\"PeriodicalId\":13678,\"journal\":{\"name\":\"Infectious disorders drug targets\",\"volume\":\"23 1\",\"pages\":\"e250822208005\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Infectious disorders drug targets\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1871526522666220825160906\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infectious disorders drug targets","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1871526522666220825160906","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Biological Importance, Therapeutic Benefits, and Analytical Aspects of Active Flavonoidal Compounds 'Corylin' from Psoralea corylifolia in the Field of Medicine.
BACKGROUND Flavonoidal class phytochemicals are the best examples of secondary metabolite found to be present in the different natural sources, including 'fruits, grains, vegetables, broccoli, tea, berries, wine, strawberries, apple, grapes, lettuce and citrus fruit. Natural products are the rich source of flavonoidal compounds present in our diet source. OBJECTIVE Flavonoidal class chemical can be sub categorized into chalcones, isoflavone, flavonols, catechin, flavones, flavanones, and anthocyanidin with respect to their basic chemical structures. Psoralea corylifolia L. belongs to the family Fabaceae is an herbal medicine used in traditional Chinese Medicine for the treatment of inflammatory disorders, bacterial infections and cancerous disorders. METHODS In the present work, scientific data has been collected from different databases and analyzed in order to know the therapeutic potential of corylin in medicine. Different scientific databases such as Google, Scopus, PubMed, Science Direct etc., have been searched to collect the needed scientific information of corylin. Scientific information of corylin has been collected in the present work in order to know the pharmacological activities and medicinal uses of corylin in the scientific fields. However, analytical techniques data of corylin have also been collected and analyzed for standardization of Psoralea corylifolia and other medicinal plants. RESULTS Scientific data analysis of research works revealed the medicinal importance of Psoralea corylifolia and its important phytoconstituents corylin in the medicine. Scientific data analysis revealed that corylin is a flavonoidal class phytochemical found to be present in the nuts of Psoralea corylifolia L. Biological importance of corylin in bone differentiation, bone growth, osteoporosis have been proven in the scientific research work. Anti-inflammatory, anti-oxidant and antitumor activity of corylin has been also mentioned in the medicine. Biological importances of corylin in hyperlipidemia, insulin resistance, atherosclerosis, hepatocellular carcinoma and neurodisorders have also been presented in this work. CONCLUSION Scientific data analysis revealed the biological importance and therapeutic potential of corylin in the medicine.
期刊介绍:
Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continues to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.