阿戈美拉汀单药治疗自闭症一例报告。

Q3 Medicine

Psychopharmacology bulletin Pub Date : 2022-10-27

Ahmed Naguy, Saxby Pridmore, Mohammed A Jamali, Alaa Eisa Hasan, Bibi Alamiri

{"title":"阿戈美拉汀单药治疗自闭症一例报告。","authors":"Ahmed Naguy, Saxby Pridmore, Mohammed A Jamali, Alaa Eisa Hasan, Bibi Alamiri","doi":"","DOIUrl":null,"url":null,"abstract":"ASD is commonly associated with a host of challenging behaviours. Pharmacotherapy is indicated if psycho-social and educational interventions fail. Atypical antipsychotics have the strongest evidence-base so far, with both risperidone and aripiprazole are FDA-approved. Unfortunately, their use is fraught with metabolic and neuro-hormonal side effects. Here, authors report on a case of ASD/mild ID with behavioural dyscontrol that failed multiple psychotropic trials and ultimately responded favourably to agomelatine monotherapy. This was achieved with excellent tolerability. This might open new venues in such complicated cases.","PeriodicalId":21069,"journal":{"name":"Psychopharmacology bulletin","volume":"52 4","pages":"100-103"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611798/pdf/","citationCount":"0","resultStr":"{\"title\":\"Agomelatine Monotherapy for Autism-A Case Report.\",\"authors\":\"Ahmed Naguy, Saxby Pridmore, Mohammed A Jamali, Alaa Eisa Hasan, Bibi Alamiri\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ASD is commonly associated with a host of challenging behaviours. Pharmacotherapy is indicated if psycho-social and educational interventions fail. Atypical antipsychotics have the strongest evidence-base so far, with both risperidone and aripiprazole are FDA-approved. Unfortunately, their use is fraught with metabolic and neuro-hormonal side effects. Here, authors report on a case of ASD/mild ID with behavioural dyscontrol that failed multiple psychotropic trials and ultimately responded favourably to agomelatine monotherapy. This was achieved with excellent tolerability. This might open new venues in such complicated cases.\",\"PeriodicalId\":21069,\"journal\":{\"name\":\"Psychopharmacology bulletin\",\"volume\":\"52 4\",\"pages\":\"100-103\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9611798/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psychopharmacology bulletin\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychopharmacology bulletin","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

ASD通常与一系列具有挑战性的行为有关。如果心理社会和教育干预失败，则需要药物治疗。到目前为止，非典型抗精神病药物有最有力的证据基础，利培酮和阿立哌唑都获得了美国食品药品监督管理局的批准。不幸的是，它们的使用充满了代谢和神经激素的副作用。在此，作者报告了一例ASD/轻度ID伴行为控制障碍的病例，该病例未通过多项精神试验，最终对阿戈美拉汀单药治疗反应良好。这是在良好的耐受性下实现的。在这种复杂的情况下，这可能会开辟新的场地。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Agomelatine Monotherapy for Autism-A Case Report.

ASD is commonly associated with a host of challenging behaviours. Pharmacotherapy is indicated if psycho-social and educational interventions fail. Atypical antipsychotics have the strongest evidence-base so far, with both risperidone and aripiprazole are FDA-approved. Unfortunately, their use is fraught with metabolic and neuro-hormonal side effects. Here, authors report on a case of ASD/mild ID with behavioural dyscontrol that failed multiple psychotropic trials and ultimately responded favourably to agomelatine monotherapy. This was achieved with excellent tolerability. This might open new venues in such complicated cases.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Psychopharmacology bulletin PHARMACOLOGY & PHARMACY-PSYCHIATRY

CiteScore

2.70

自引率

0.00%

发文量

期刊介绍： Information not localized