多感觉刺激和启动(MuSSAP)在4-10月龄婴儿单侧脑损伤中的应用:一项试点随机临床试验

IF 1.3 4区 医学 Q3 REHABILITATION
Anke P M Verhaegh, Brenda E Groen, Pauline B M Aarts, Raymond van Ee, Michèl A A P Willemsen, Marijtje L A Jongsma, Maria W G Nijhuis-van der Sanden
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引用次数: 1

摘要

目的:探讨早期强化上肢干预(EI-UL)与EI-UL联合多感觉刺激与启动(MuSSAP)训练对单侧脑损伤婴儿手操作能力提高的影响。方法:采用前瞻性随机临床试验,采用干预前、干预后及随访测量(T0、T1、T2)。16名患有单侧脑损伤的婴儿(矫正年龄为4-10个月)接受了基于家庭的视频指导干预。8名婴儿接受EI-UL, 8名婴儿接受EI-UL并进行综合MuSSAP训练。主要结果为婴儿手部评估(HAI)评分。此外,我们还探讨了两组在目标导向运动启动方面的影响,以及EI-UL联合MuSSAP训练组在注意力方面的影响。结果:各组间HAI评分差异无统计学意义。总体而言,HAI“影响手评分”在T0和T1之间增加(p = 0.001, Cohen’s d = 1.04),在T0和T2之间增加(p < 0.001, Cohen’s d = 1.28);HAI“双手测量”在T0和T1之间(p < 0.001, Cohen’s d = 1.72)和T0和T2之间(p < 0.001, Cohen’s d = 1.81)增加。在干预开始时,6名婴儿(两组各3名)没有表现出目标导向对抗性上肢运动的开始。在干预期间,一名接受EI-UL的婴儿和三名接受EI-UL并结合MuSSAP训练的婴儿开始发起目标导向的运动。结论:两种干预措施均能提高单侧脑损伤患儿的操作能力。我们假设综合的MuSSAP训练可以促进注意力和对抗性上肢目标定向运动的启动。该试验注册号为NCT05533476)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Multisensory Stimulation and Priming (MuSSAP) in 4-10 Months Old Infants with a Unilateral Brain Lesion: A Pilot Randomised Clinical Trial.

Multisensory Stimulation and Priming (MuSSAP) in 4-10 Months Old Infants with a Unilateral Brain Lesion: A Pilot Randomised Clinical Trial.

Multisensory Stimulation and Priming (MuSSAP) in 4-10 Months Old Infants with a Unilateral Brain Lesion: A Pilot Randomised Clinical Trial.

Multisensory Stimulation and Priming (MuSSAP) in 4-10 Months Old Infants with a Unilateral Brain Lesion: A Pilot Randomised Clinical Trial.

Aim: To explore the effect of an Early Intensive-Upper Limb intervention (EI-UL) compared to EI-UL with integrated Multisensory Stimulation And Priming (MuSSAP) training on improving manual ability in infants with a unilateral brain lesion.

Method: A pilot randomised clinical trial with pre- and postintervention and follow-up measurements (T0, T1, and T2) was conducted. Sixteen infants with a unilateral brain lesion (corrected age is 4-10 months) received home-based intervention with video coaching. Eight infants received EI-UL and eight infants received EI-UL with integrated MuSSAP training. Primary outcome was the Hand Assessment for Infants (HAI) score. Additionally, effects were explored on initiation of goal-directed movements in both groups and on attention in the EI-UL with integrated MuSSAP training group.

Results: No significant group differences in HAI scores were found. Overall, HAI 'Affected hand score' increased between T0 and T1 (p = 0.001, Cohen's d = 1.04) and between T0 and T2 (p < 0.001, Cohen's d = 1.28); and the HAI 'Both Hands Measure' increased between T0 and T1 (p < 0.001, Cohen's d = 1.72) and between T0 and T2 (p < 0.001, Cohen's d = 1.81). At the start of the intervention, six infants (three in both groups) did not demonstrate initiation of goal-directed contralesional upper limb movements. During the intervention one infant receiving EI-UL and all three infants receiving EI-UL with integrated MuSSAP training started to initiate goal-directed movements.

Conclusion: The results suggest manual ability of infants with unilateral brain lesion improved with both interventions. We hypothesize that the integrated MuSSAP training may facilitate attention and initiation of contralesional upper limb goal-directed movements. This trial is registered with NCT05533476).

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来源期刊
CiteScore
2.50
自引率
6.70%
发文量
121
审稿时长
>12 weeks
期刊介绍: Occupational Therapy International is a peer-reviewed journal, publishing manuscripts that reflect the practice of occupational therapy throughout the world. Research studies or original concept papers are considered for publication. Priority for publication will be given to research studies that provide recommendations for evidence-based practice and demonstrate the effectiveness of a specific treatment method. Single subject case studies evaluating treatment effectiveness are also encouraged. Other topics that are appropriate for the journal include reliability and validity of clinical instruments, assistive technology, community rehabilitation, cultural comparisons, health promotion and wellness.
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