一例罕见的包裹性血管浸润性甲状腺滤泡癌头皮转移病例

IF 1 4区 医学 Q3 OTORHINOLARYNGOLOGY
Ent-Ear Nose & Throat Journal Pub Date : 2025-03-01 Epub Date: 2023-01-22 DOI:10.1177/01455613231154063
Masataka Kojima, Shin Ito, Mako Saikawa, Kazunori Kajino, Naomi Ohtsuji, Fumihiko Matsumoto, Ryuzaburo Higo
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引用次数: 0

摘要

甲状腺癌的皮肤转移极为罕见;然而,头皮是滤泡性甲状腺癌(FTC)皮肤转移的常见部位。我们报告了一例77岁男性患者的头皮血肿病例。打孔活检标本的组织病理学检测显示,皮下形成的滤泡结构与甲状腺中的滤泡结构相似。使用甲状腺转录因子-1(TTF-1)和配对盒基因家族 8(PAX8)进行的免疫组化检查发现了 FTC 转移。我们同时进行了甲状腺全切除术和头皮病灶切除术,并在术后进行了放射性碘治疗。根据囊外扩展和血管侵犯情况,甲状腺原发病灶被诊断为 FTC。治疗后,患者未再复发。当怀疑甲状腺癌有头皮转移时,我们建议进行包括原发肿瘤和头皮转移灶在内的全切除术,以改善预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Rare Case of Scalp Metastasis from Encapsulated Angioinvasive Follicular Thyroid Carcinoma.

Cutaneous metastases from thyroid carcinomas are extremely rare; however, the scalp is a common site for cutaneous metastases from follicular thyroid carcinomas (FTCs). We report the case of a 77-year-old male patient with a blood-rich scalp lesion. Histopathological tests of punch biopsy specimens revealed subcutaneous well-formed follicular structures that were similar to those found in the thyroid gland. Immunohistochemistry using thyroid transcription factor-1 (TTF-1) and paired-box gene family 8 (PAX8) revealed an FTC metastasis. We performed total thyroidectomy and resection of the scalp lesion at the same time and administered postoperative radioactive iodine treatment. The primary thyroid lesion was diagnosed as an FTC based on extracapsular extension and vessel invasion. The patient has not experienced disease recurrence since the treatment. When scalp metastasis of thyroid carcinoma is suspected, we recommend total extirpation, including the primary tumor and scalp metastasis, for an improved prognosis.

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来源期刊
Ent-Ear Nose & Throat Journal
Ent-Ear Nose & Throat Journal 医学-耳鼻喉科学
CiteScore
3.20
自引率
0.00%
发文量
385
审稿时长
6-12 weeks
期刊介绍: Ear, Nose & Throat Journal provides practical, peer-reviewed original clinical articles, highlighting scientific research relevant to clinical care, and case reports that describe unusual entities or innovative approaches to treatment and case management. ENT Journal utilizes multiple channels to deliver authoritative and timely content that informs, engages, and shapes the industry now and into the future.
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