Amirhossein Behzadi, Sadegh Imani, Niloofar Deravi, Zahra Mohammad Taheri, Fatemeh Mohammadian, Zahra Moraveji, Sepideh Shavysi, Motahareh Mostafaloo, Fateme Soleimani Hadidi, Sepehr Nanbakhsh, Sepehr Olangian-Tehrani, Mohammad Hesam Marabi, Parisa Behshood, Mohadeseh Poudineh, Ali Kheirandish, Kimia Keylani, Pooya Behfarnia
{"title":"Melissa officinalis L.的抗病毒潜力：文献综述。","authors":"Amirhossein Behzadi, Sadegh Imani, Niloofar Deravi, Zahra Mohammad Taheri, Fatemeh Mohammadian, Zahra Moraveji, Sepideh Shavysi, Motahareh Mostafaloo, Fateme Soleimani Hadidi, Sepehr Nanbakhsh, Sepehr Olangian-Tehrani, Mohammad Hesam Marabi, Parisa Behshood, Mohadeseh Poudineh, Ali Kheirandish, Kimia Keylani, Pooya Behfarnia","doi":"10.1177/11786388221146683","DOIUrl":null,"url":null,"abstract":"<p><p>The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass (<i>Melissa officinalis</i>) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of <i>Melissa officinalis</i> and its effect on viral diseases. More in vitro and in vivo studies are needed to determine <i>Melissa officinaliss</i> underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. Also, due to the usefulness and lack of side effects, it can be used more as a complementary medicine.</p>","PeriodicalId":19396,"journal":{"name":"Nutrition and Metabolic Insights","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/81/47/10.1177_11786388221146683.PMC9841880.pdf","citationCount":"0","resultStr":"{\"title\":\"Antiviral Potential of Melissa officinalis L.: A Literature Review.\",\"authors\":\"Amirhossein Behzadi, Sadegh Imani, Niloofar Deravi, Zahra Mohammad Taheri, Fatemeh Mohammadian, Zahra Moraveji, Sepideh Shavysi, Motahareh Mostafaloo, Fateme Soleimani Hadidi, Sepehr Nanbakhsh, Sepehr Olangian-Tehrani, Mohammad Hesam Marabi, Parisa Behshood, Mohadeseh Poudineh, Ali Kheirandish, Kimia Keylani, Pooya Behfarnia\",\"doi\":\"10.1177/11786388221146683\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass (<i>Melissa officinalis</i>) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of <i>Melissa officinalis</i> and its effect on viral diseases. More in vitro and in vivo studies are needed to determine <i>Melissa officinaliss</i> underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. 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Antiviral Potential of Melissa officinalis L.: A Literature Review.
The use of synthetic drugs has increased in recent years; however, herbal medicine is yet more trusted among a huge population worldwide; This could be due to minimal side effects, affordable prices, and traditional beliefs. Lemongrass (Melissa officinalis) has been widely used for reducing stress and anxiety, increasing appetite and sleep, reducing pain, healing wounds, and treating poisonous insect bites and bee stings for a long time. Today, research has shown that this plant can also fight viruses including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Herpes Simplex Virus (HSV), and Human Immunodeficiency Virus (HIV) through various mechanisms such as inhibiting HSV-1 from binding to host cell, inhibiting HSV-1 replication during the post-adsorption or inhibiting main protease and spike protein of SARS-CoV-2, furthermore, be effective in treating related diseases. This Review investigated the antiviral properties of Melissa officinalis and its effect on viral diseases. More in vitro and in vivo studies are needed to determine Melissa officinaliss underlying mechanism, and more randomized controlled trials should be done to identify its effect in humans. Also, due to the usefulness and lack of side effects, it can be used more as a complementary medicine.
期刊介绍：
Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focusing on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels. This journal welcomes new manuscripts for peer review on the following topics: Nutrition, including the biochemistry of metabolism, Exercise and associated physical processes, Clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes, Research at the molecular, cellular and organismal levels, Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.
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