糖尿病的实验方法。

Pub Date : 2022-12-01 DOI:10.5152/eurasianjmed.2022.22304
Muhammed Yayla, Damla Binnetoğlu
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引用次数: 0

摘要

糖尿病是当今最常见的健康问题之一,是一种以高血糖为特征的严重、慢性、复杂疾病。如今,人们正在开发糖尿病实验模型,以深入研究现有的糖尿病、改进糖尿病药物或开发新药物。迄今为止,创建糖尿病实验模型的方案是根据不同的时间间隔和各种因素最终确定的。通过这些可在体内和体外设计的模型,可以创造出类似于 1 型和 2 型糖尿病的图景。在这篇综述中,我们旨在根据现有文献介绍目前使用的所有糖尿病实验模型的方法、优点和缺点。
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Experimental Approaches to Diabetes Mellitus.

One of the most common health problems today, diabetes is a serious, chronic, and complex disease characterized by high blood glucose levels. Nowadays, experimental diabetes models are being developed to study existing diabetes in depth, to improve diabetes medications, or to develop new medications. The protocols developed to date to create an experimental diabetes model are finalized in different time intervals and depending on various factors. With these models, which can be designed in vivo and in vitro, a picture similar to type 1 and type 2 diabetes can be created. In this review, we aimed to present the methodology, advantages, and disadvantages of all currently used experimental diabetes models in the light of current literature.

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