壳聚糖在制药中的应用综述。

2区医学 Q1 Biochemistry, Genetics and Molecular Biology

Reviews of Physiology Biochemistry and Pharmacology Pub Date : 2023-01-01 DOI:10.1007/112_2021_69

Olimpia Daniela Frenț, Laura Vicaș, Tunde Jurca, Stefania Ciocan, Narcis Duteanu, Annamaria Pallag, Mariana Muresan, Eleonora Marian, Adina Negrea, Otilia Micle

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引用次数: 3

摘要

壳聚糖是一种广泛存在于自然界的天然多糖。它在制药领域具有许多独特和吸引人的特性:可生物降解、安全、低过敏性、与人体生物相容性、无毒性、具有抗胆固醇、抗菌和抗真菌作用。本文综述了壳聚糖在制备各种剂型时应考虑的物理、化学、机械、粘接等性能。制备壳聚糖药物的方法非常广泛，本研究只介绍了几种最常用的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Review: Uses of Chitosan in Pharmaceutical Forms.

Chitosan is a natural polysaccharide widespread in nature. It has many unique and attractive properties for the pharmaceutical field: it is biodegradable, safe, hypoallergenic, biocompatible with the body, free of toxicity, with proven anticholesterolemic, antibacterial, and antimycotic action. In this review we highlighted the physical, chemical, mechanical, mucoadhesive, etc. properties of chitosan to be taken into account when obtaining various pharmaceutical forms. The methods by which the pharmaceutical forms based on chitosan are obtained are very extensive, and in this study only the most common ones were presented.

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来源期刊

Reviews of Physiology Biochemistry and Pharmacology 医学-生化与分子生物学

CiteScore

11.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.