缺囊性隐球菌脑膜炎：诊断难题。

IF 1 Q4 INFECTIOUS DISEASES

Journal of Global Infectious Diseases Pub Date : 2022-11-15 eCollection Date: 2022-10-01 DOI:10.4103/jgid.jgid_255_21

Trupti Shende, Gagandeep Singh, Immaculata Xess, Swati Khullar, Renu Kumari Yadav, Reshu Agarwal, M Vasantha Padma Srivastava

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引用次数: 0

摘要

隐球菌病是一种严重的全身性真菌病。在过去 40 年中，其发病率不断上升。新型隐球菌可在免疫力低下和免疫力正常的患者中引起局部感染或播散感染。常见的是荚膜型，可通过印度墨水制剂或抗原检测进行诊断。然而，无囊型非常罕见，需要高度怀疑才能正确诊断。在本文中，我们介绍了一例隐球菌脑膜炎病例，该病例是由一株无囊菌株引起的，患者表面上免疫功能正常，未证实有免疫缺陷。此类病例对临床医生和微生物学家来说都是一个诊断难题。

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Capsule-Deficient Cryptococcal Meningitis: A Diagnostic Conundrum.

Cryptococcosis is a serious systemic mycosis. Its incidence has escalated in the past four decades. Cryptococcus neoformans causes localized or disseminated infection in immunocompromised and immunocompetent patients. The capsulated form is commonly encountered which can be diagnosed on an India ink preparation or antigen detection. However, the noncapsulated forms are very rare and require a high index of suspicion for correct diagnosis. Herein, we present a case of cryptococcal meningitis due to a noncapsulated strain in an apparently immunocompetent patient with no proven immunodeficiencies along with review of world literature. Such cases are a diagnostic challenge for the clinician as well as microbiologist.

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来源期刊

Journal of Global Infectious Diseases INFECTIOUS DISEASES-

CiteScore

3.30

自引率

0.00%

发文量

审稿时长

29 weeks

期刊介绍： JGID encourages research, education and dissemination of knowledge in the field of Infectious Diseases across the world thus promoting translational research by striking a synergy between basic science, clinical medicine and public health. The Journal intends to bring together scientists and academicians in Infectious Diseases to promote translational synergy between Laboratory Science, Clinical Medicine and Public Health. The Journal invites Original Articles, Clinical Investigations, Epidemiological Analysis, Data Protocols, Case Reports, Clinical Photographs, review articles and special commentaries. Students, Residents, Academicians, Public Health experts and scientists are all encouraged to be a part of this initiative by contributing, reviewing and promoting scientific works and science.