展望灵长类神经科学研究的未来

Peter Janssen , Tadashi Isa , Jose Lanciego , Kirk Leech , Nikos Logothetis , Mu-Ming Poo , Anna S. Mitchell
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引用次数: 3

摘要

未来涉及非人类灵长类动物(NHP)的神经科学和生物医学项目对于我们理解哺乳动物中枢神经系统的复杂性和功能仍然至关重要。在这样做的过程中,必须允许NHP神经科学研究人员结合最先进的技术,包括使用新型病毒载体、基因治疗和转基因方法来回答只有在NHP研究模型中才能解决的持续和新出现的研究问题。这篇观点文章捕捉了这些新兴技术以及它们可以解决的一些具体研究问题。与此同时,我们强调了目前对全球NHP研究和合作的一些警告,包括缺乏共同的NHP研究伦理和监管框架,涉及动物运输和出口的限制,以及反对NHP研究的活动家团体的持续影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Visualizing advances in the future of primate neuroscience research

Future neuroscience and biomedical projects involving non-human primates (NHPs) remain essential in our endeavors to understand the complexities and functioning of the mammalian central nervous system. In so doing, the NHP neuroscience researcher must be allowed to incorporate state-of-the-art technologies, including the use of novel viral vectors, gene therapy and transgenic approaches to answer continuing and emerging research questions that can only be addressed in NHP research models. This perspective piece captures these emerging technologies and some specific research questions they can address. At the same time, we highlight some current caveats to global NHP research and collaborations including the lack of common ethical and regulatory frameworks for NHP research, the limitations involving animal transportation and exports, and the ongoing influence of activist groups opposed to NHP research.

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